Volume 11 Supplement 1

16th International Conference on Human Retroviruses: HTLV and Related Viruses

Meeting abstracts

Edited by Benoit Barbeau

Publication of this supplement was funded by the Canadian Institutes of Health Research (#201206). The Supplement Editor declares that he has no competing interests.

16th International Conference on Human Retroviruses: HTLV and Related Viruses. Go to conference site.

Montreal, Canada26-30 June 2013

Page 3 of 5

Contribution of galvanic vestibular stimulation for the diagnosis of HAM/TSP

Authors: Luciana Cunha, Ludimila Labanca, Anna Bárbara F Carneiro-Proietti, Lucas N Carvalho, Daniele R Fernandes, Ana Lúcia B Starling and Denise U Gonçalves

Citation: Retrovirology 2014 11(Suppl 1):P27

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HTLV-1 associated bronchiectasis among Indigenous Australians is associated with higher HTLV-1 proviral loads: Results of a prospective case-control study

Authors: Lloyd Einsiedel, Olivier Cassar, Emma Goeman, Tim Spelman and Antoine Gessain

Citation: Retrovirology 2014 11(Suppl 1):P28

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Early diagnosis of HTLV-1-associated myelopathy (HAM/TSP) in HTLV-1 carrier clinic

Authors: Toshio Matsuzaki, Ryuji Kubota, Hiroshi Takashima and Shuji Izumo

Citation: Retrovirology 2014 11(Suppl 1):P29

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Change in timed walk as primary outcome measure of treatment response in HAMLET-P: HAM/TSP MuLticentre Efficacy trial-Prednisolone

Authors: Fabiola Martin, Eisuke Inoue, Maria Fernanda Rios Grassi, Ramon de Almeida Kruschewsky, Irene Cortese, Marcus T Silva, Steve Jacobson, Bernardo Galvão-Castro, Yoshihisa Yamano, Graham Taylor and John Martin Bland

Citation: Retrovirology 2014 11(Suppl 1):P30

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A proof of concept study of Infliximab for the treatment of HTLV-1-associated myelopathy

Authors: Fabiola Martin, Hannah Castro, Carolyn Gabriel, Adine Adonis, Alexandra Fedina, Linda Harrison, Liz Brodnicki, Maria A Demontis, Abdel G Babiker, Jonathan N Weber, Charles RM Bangham and Graham P Taylor

Citation: Retrovirology 2014 11(Suppl 1):P31

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Neuropsychological assessment in HTLV-1 infection: Preliminary data of a comparative study among depression and neurocognitive impairments

Authors: Maria Rita Polo Gascón, Yolanda Marques Mazzaro, Claudio Garcia Capitão, Vilma BL Ferreira Jardim, Guilherme Sciascia Olival, José Vidal Bermudez, Casseb Jorge, Smid Jerusa, Penalva Oliveira and Augusto César

Citation: Retrovirology 2014 11(Suppl 1):P32

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Treatment of patients with HTLV-1-associated myelopathy with methotrexate

Authors: S Ahmed, A Adonis, S Hilburn, MA Demontis, A Fedina, J Haddow, C Gabriel, S Fidler and GP Taylor

Citation: Retrovirology 2014 11(Suppl 1):P33

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HTLV-1 proviral load in adult T-cell leukemia/lymphoma (ATLL) patients from non-endemic regions of Argentina

Authors: Andrea Mangano, María Saliba Pineda, Patricia Costantini, María Belén Bouzas, Cecilia Chidid, Griselda Di Stefano, Ana Inés Varela, Natalia Altamirano, Luciana Tadey, Lilia Mammana, Paula Aulicino, Liliana Olivares and Luisa Sen

Citation: Retrovirology 2014 11(Suppl 1):P34

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Medical conditions, social and neurological patients of the T-lymphotropic virus humanities-HTLV I

Authors: GLC Gaspar, MAS Souza, T Masteguim, S Matta, J Casseb, GS Olival, R Marcusso and ACP Oliveira

Citation: Retrovirology 2014 11(Suppl 1):P35

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HTLV-1 proviral load as an indicative marker of HAM/TSP: a systematic review of studies of patients with HAM/TSP

Authors: Shiva Shaan Bassi, Raimundo Coutinho Jr, Viviana Nilla Olavarria, Fabiola Martin, Bernardo Galvão-Castro and Maria Fernanda Rios Grassi

Citation: Retrovirology 2014 11(Suppl 1):P36

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HAM/TSP in relatives of HAM/TSP cases and in relatives of asymptomatic HTLV-1 carriers

Authors: Carolina Alvarez, Kristien Verdonck, Martín Tipismana, Michael Talledo, Jason Rosado, Daniel Clark, Johan Van Weyenbergh, Anne-Mieke Vandamme and Eduardo Gotuzzo

Citation: Retrovirology 2014 11(Suppl 1):P37

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Managing HAM/TSP with Fampridine

Authors: M Marcio Menna-Barreto

Citation: Retrovirology 2014 11(Suppl 1):P38

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Effects of valproate on Tax and HBZ expression in ex vivo cultured ATL cells

Authors: Gildas Belrose, Hélène Gazon, Jean-Côme Meniane, Stéphane Olindo, Jean-Michel Mesnard, Jean-Marie Péloponèse and Raymond Césaire

Citation: Retrovirology 2014 11(Suppl 1):P39

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HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP)-like disease and toxic epidermal necrolysis (TEN)-like disease in HTLV-1 Tax transgenic mice

Authors: Takeo Ohsugi, Makoto Wakamiya, Saki Morikawa, Kumi Matsuura, Toshio Kumasaka and Kazunari Yamaguchi

Citation: Retrovirology 2014 11(Suppl 1):P40

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Co-infection of Mandrills with SIVmnd and STLV-1: implications for clinical outcome

Authors: Sandrine Souquière and Mirdad Kazanji

Citation: Retrovirology 2014 11(Suppl 1):P41

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Carrier model of HTLV-1 infection in humanized NOG mice

Authors: Kenta Tezuka, Mami Tei, Takaharu Ueno, Runze Xun and Jun-ichi Fujisawa

Citation: Retrovirology 2014 11(Suppl 1):P42

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Inhibition of ATL development in humanized mouse model by AZT/INF treatment

Authors: Kenta Tezuka, Mami Tei, Takaharu Ueno, Runze Xun, Hidekatu Iha and Jun-ichi Fujisawa

Citation: Retrovirology 2014 11(Suppl 1):P43

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A novel HSP90 inhibitor, 17-DMAG, induces Tax down-regulation and its oral administration to ATL-model mice intervenes against the infiltration property of the ATL-like lymphocytes and provides extended survival period

Authors: Emi Ikebe, Akira Kawaguchi, Kenta Tezuka, Shinya Taguchi, Satoshi Hirose, Takashi Matsumoto, Takahiro Mitsui, Kazuyo Senba, Akira Nishizono, Mitsuo Hori, Hiroo Hasegawa, Yasuaki Yamada, Takaharu Ueno, Yuetsu Tanaka, Hirofumi Sawa, William Hall…

Citation: Retrovirology 2014 11(Suppl 1):P44

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Epidemiological features of BLV natural infection

Authors: Marina Lomonaco, Irene Alvarez, Cecilia Martínez, Natalia Porta, Ramiro Merlini, Hugo Carignano, Gerónimo Gutiérrez and Karina Trono

Citation: Retrovirology 2014 11(Suppl 1):P45

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Egg yolk antibodies (IgY) against Bovine Leukemia Virus

Authors: Cecilia Martínez, Gerónimo Gutiérrez, Irene Alvarez, Natalia Porta, Marina Lomónaco, Andrés Wigdorovitz, Pablo Chacana and Karina Trono

Citation: Retrovirology 2014 11(Suppl 1):P46

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Molecular characterization of HTLV-1 and HTLV-2 and routes of virus transmission in HIV-infected patients from the southeastern and southern Brazil

Authors: Mariana C Magri, Luis FM Brígido, Helena K Morimoto and Adele Caterino-de-Araujo

Citation: Retrovirology 2014 11(Suppl 1):P47

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Inferences about global scenario of HTLV-1 infection using data mining of viral sequences

Authors: Thessika HA Araujo, Fernanda K Barreto, Aline CAM Miranda and Luiz CJ Alcantara

Citation: Retrovirology 2014 11(Suppl 1):P48

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The origin of HTLV-1 in the South Bahia by phylogenetic, mitochondrial DNA and β-globin analysis

Authors: Sandra R Gadelha, Milena M Aleluia, Marco AG Mello, Filipe FA Rego, Lucas S Pereira, Bernardo Galvão-Castro, Marilda Gonçalves, Sandra MB Sousa and Luiz C Alcântara

Citation: Retrovirology 2014 11(Suppl 1):P49

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Interfamilial transmission of HTLV-1 in the South of Bahia, Brazil

Authors: Sandra R Gadelha, Milena M Aleluia, Marco AG Mello, Filipe FA Rego, Lucas S Pereira, Bernardo Galvão-Castro, Marilda Gonçalves, Sandra MB Sousa and Luiz C Alcântara

Citation: Retrovirology 2014 11(Suppl 1):P50

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Neurological outcomes analysis of HTLV-1 seropositive patients of the Interdisciplinary Research HTLV Group (GIPH) cohort, Brazil

Authors: Débora B Reiss, Gabriela S Freitas, Rafael HC Bastos, Mariana A de Souza, Cláudia LF Horiguchi, Marina L Martins, Anísia SD Ferreira, Ana Lúcia B Starling, Luiz Cláudio F Romanelli and Anna Bárbara FC Proietti

Citation: Retrovirology 2014 11(Suppl 1):P51

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Assessing the impact of counseling HTLV-1 seropositive women on vertical transmission in the GIPH cohort study, Brazil

Authors: Mariana A de Souza, Cláudia LF Horiguchi, Gabriela S Freitas, Rafael HC Bastos, Débora B Reiss, Marina L Martins, Maria Sueli N Lopes and Anna Bárbara FC Proietti

Citation: Retrovirology 2014 11(Suppl 1):P52

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HTLV-1 and 2 in family groups in Belo Horizonte, Brazil: prevalence and routes of contamination

Authors: Cláudia LF Horiguchi, Mariana A de Souza, Débora B Reiss, Gabriela S Freitas, Rafael HC Bastos, Marina L Martins, Fernando A Proietti, Luiz Cláudio F Romanelli, Maria Sueli N Lopes and Anna Bárbara F Carneiro-Proietti

Citation: Retrovirology 2014 11(Suppl 1):P53

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Human T-cell lymphotropic virus type 1 infection among U.S. Thalassemia patients

Authors: William M Switzer, Anupama Shankar, Sean R Trimble, Alexis A Thompson, Patricia J Giardina, Alan R Cohen, Thomas D Coates, Elliott Vichinsky, Ellis J Neufeld, Jeanne M Boudreaux and Walid Heneine

Citation: Retrovirology 2014 11(Suppl 1):P54

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The UK human T-cell lymphotropic virus cohort: Unique perspectives from a decade of follow up

Authors: Katy Davison, Su Brailsford, Patricia Hewitt, Jana Haddow and Graham Taylor

Citation: Retrovirology 2014 11(Suppl 1):P55

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HTLV-1 molecular epidemiology in central Australia: Two distinctive HTLV-1 Subtype C lineages in Indigenous Australians

Authors: Olivier Cassar, Lloyd Einsiedel, Philippe V Afonso and Antoine Gessain

Citation: Retrovirology 2014 11(Suppl 1):P56

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High frequency of HTLV-1 infection in Bantus and Pygmies from rural Cameroon bitten by non-human primates during hunting

Authors: Claudia Filippone, Edouard Betsem, Sylviane Bassot, Patricia Tortevoye, Alain Froment, Arnaud M Fontanet and Antoine Gessain

Citation: Retrovirology 2014 11(Suppl 1):P57

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Sero-prevalence of HTLV 1/2 and HCV in paired mother and children from Malawi as well as systematic review and meta-analysis of HTLV-1/2 and HCV of data available on women and children living in Africa

Authors: James M Fox, Robert Newton, Marija Bedaj, John Martin Bland, Nora Mutalima and Fabiola Martin

Citation: Retrovirology 2014 11(Suppl 1):P58

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Colostrum replacer and bovine leukaemia virus sero-positivity

Authors: Bhudipa Choudhury, Christopher Finnegan, Jean-Pierre Frossard, Chris Venables and Falko Steinbach

Citation: Retrovirology 2014 11(Suppl 1):P59

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Epidemiology of Human T-cell lymphotropic viruses (HTLV) in England and Wales, 2003-2012

Authors: Sara E Croxford, Valerie C Delpech, Jennifer HC Tosswill, Katy Davison and Graham P Taylor

Citation: Retrovirology 2014 11(Suppl 1):P60

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Seroprevalence of Human T-lymphotropic virus type-1 and -2 infections among first-time United States Blood Donors 2000-2009

Authors: Yun Brenda Chang, Zhanna Kaidarova, Daniel Hindes, Marjorie Bravo, Nancy Kiely, Hany Kamel, Denise Dubay, Barbara Hoose and Edward L Murphy

Citation: Retrovirology 2014 11(Suppl 1):P61

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Human T cell lymphotropic virus type 1 (HTLV-1) infection increases the CD4 count in human immunodeficiency virus type 1 (HIV-1) infected patients submitted to antiretroviral therapy (ARV)

Authors: Filipe FA Rego, Luiz CJ Alcantara and Tulio de Oliveira

Citation: Retrovirology 2014 11(Suppl 1):P62

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HTLV-1 Tax peptide-carrying polyion complex nanoparticles induce potent cellular immunity in mice

Authors: Tomofumi Uto, Takami Akagi, Mitsuru Akashi and Masanori Baba

Citation: Retrovirology 2014 11(Suppl 1):P63

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The MHC Class II transactivator CIITA inhibits Tax-1-mediated HTLV-1 expression and NF-kB activation

Authors: Rawan Abdallah, Greta Forlani, Roberto S Accolla and Giovanna Tosi

Citation: Retrovirology 2014 11(Suppl 1):P64

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Impaired T cell receptor signaling in HTLV-1-infected CD4+ cells from HAM/TSP patients

Authors: Ryuji Kubota, Hiroshi Takashima and Shuji Izumo

Citation: Retrovirology 2014 11(Suppl 1):P65

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Impairment of humoral and cellular immune response to tetanus toxoid in HTLV-1 infected individuals

Authors: Anselmo S Souza, Camila F Amorim, Natália Carvalho, Silvane B Santos and Edgar M Carvalho

Citation: Retrovirology 2014 11(Suppl 1):P66

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Immune response, proviral load and serologic markers of neurologic disease expression in HTLV-1 infection

Authors: Silvane Santos, Cristina Toledo, Anselmo Souza, Davi Tanajura, Marshall Glesby and Edgar M Carvalho

Citation: Retrovirology 2014 11(Suppl 1):P67

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Modulation of the immune response in HTLV-1-infections by SM29 antigen in vitro is dependent of IL-10, TGF-β and CTLA-4

Authors: Luciane Mota Lima, Silvane Braga Santos, Ricardo Riccio Oliveira, Luciana Santos Cardoso, Sergio Costa Oliveira, Alfredo Miranda Góes, Alex Loukas, Edgar M De Carvalho and Maria Ilma Araújo

Citation: Retrovirology 2014 11(Suppl 1):P68

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Integration site analysis in Japanese HTLV-1 infected asymptomatic carriers and HAM/TSP patients

Authors: Heather Niederer, Daniel Laydon, Anat Melamed, Marjet Elemans, Becca Asquith, Masao Matsuoka and Charles Bangham

Citation: Retrovirology 2014 11(Suppl 1):P69

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Murine FLT3 ligand-derived dendritic cell-mediated early immune responses are critical to controlling cell-free human T cell leukemia virus type 1 infection

Authors: Saifur Rahman, Zafar K Khan, Brian Wigdahl, Stephen Jennings, Frederic Tangy and Pooja Jain

Citation: Retrovirology 2014 11(Suppl 1):P70

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Depletion of dendritic cells enhances susceptibility to cell-free infection of human T cell leukemia virus type 1 in CD11c-diphtheria toxin receptor transgenic mice

Authors: Saifur Rahman, Sharrón L Manuel, Zafar K Khan, Brian Wigdahl, Edward Acheampong, Frederic Tangy and Pooja Jain

Citation: Retrovirology 2014 11(Suppl 1):P71

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Impact of dendritic cells and adjuvant on the in vivo immunogenicity of HTLV-1 Tax 11-19 epitope in hybrid HLA-A2.1/DTR transgenic mice

Authors: Divya Sagar, Shet Masih, Todd Schell, Saifur Rahman, Pooja Jain and Zafar K Khan

Citation: Retrovirology 2014 11(Suppl 1):P72

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Generation of direct antigen-sandwich enzyme-linked immune-sorbent assays (ELISA) for quantitation of HTLV-1 gp46, p24, Tax and related host cellular antigens OX40, OX40L and CD25

Authors: Reiko Tanaka, Yoshiaki Takahashi, Akira Kodama, Mineki Saito and Yuetsu Tanaka

Citation: Retrovirology 2014 11(Suppl 1):P73

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HLA-G 3142C/G polymorphism is related to development of symptoms in HTLV-1 infected individuals

Authors: Daiani C Cilião-Alves, Maurício C Rocha-Junior, Rodrigo Haddad, Virgínia MD Wagatsuma, Osvaldo M Takayanagui, Dimas T Covas, Simone Kashima and Eduardo A Donadi

Citation: Retrovirology 2014 11(Suppl 1):P74

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Genes related to antiviral activity are differentially expressed in CD4⁺ T cell in HAM/TSP patients

Authors: Mariana T Pinto, Tathiane M Malta, Daniel G Pinheiro, Evandra S Rodrigues, Rodrigo A Panepucci, Alessandra P Sousa, Kelen CR Malmegrim, Patricia VB Palma, Osvaldo M Takayanagui, Dimas T Covas and Simone Kashima

Citation: Retrovirology 2014 11(Suppl 1):P75

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Do African and European ancestry and polymorphism of HLA class I play an important role in controlling HTLV-1 proviral load in admixed cohorts from Salvador, Brazil?

Authors: Viviana Nilla Olavarria, Eduardo José Melo dos Santos, Sidney Emanuel Batista dos Santos, Fernanda Grassi, Ramon Kruchewesky, Luís Cristóvão de Moraes Sobrino Pôrto, Xiaojan Gao, Mary Carrington and Bernardo Galvão-Castro

Citation: Retrovirology 2014 11(Suppl 1):P76

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16th International Conference on Human Retroviruses: HTLV and Related Viruses

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