Volume 6 Supplement 3

AIDS Vaccine 2009

Meeting abstracts

Edited by Anna Laura Ross

AIDS Vaccine 2009. Go to conference site.

Paris, France19-22 October 2009

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Page 1 of 10

Content type: Oral presentation

S01-04 OA. Phenotypic analyses of CD8+ T cells that mediate virus inhibition from HIV-1 vaccinees and HIV-1+ virus controllers

Authors: SA Freel, PK Chattopadhyay, L Lamoreaux, D Zarkowsky, RG Overman, C Ochsenbauer-Jambor, JC Kappes, CK Cunningham, TN Denny, KJ Weinhold, G Ferrari, RA Koup, BS Graham, BF Haynes, M Roederer and GD Tomaras

Citation: Retrovirology 2009 6(Suppl 3):O1

Published on: 22 October 2009
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P01-01. The blood transcriptional response to early acute HIV infection is transient and responsive to antiretroviral therapy

Authors: JA Skinner, M Sharma, N Baldwin, B Lemoine, D Blankenship, EB De Vol, A Mejias, O Ramilo, M Cohen, N Letvin, D Goldstein, K Soderberg, TN Denny, K Shianna, A McMichael, B Haynes…

Citation: Retrovirology 2009 6(Suppl 3):P1

Published on: 22 October 2009
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S011-05 OA. HLA-A*7401 is associated with protection from HIV-1 acquisition and disease progression in Mbeya, Tanzania

Authors: RN Koehler, AM Walsh, E Saathoff, JR Currier, CT Bautista, N Moqueet, S Ratto-Kim, L Maboko, M Hoelscher, ML Robb, NL Michael, FE McCutchan, JH Kim and GH Kijak

Citation: Retrovirology 2009 6(Suppl 3):O2

Published on: 22 October 2009
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P01-02. Anti-inflammatory and regulatory mechanisms provide the context for an effective CD8+ T cell response in live-attenuated immunized animals

Authors: M Genescà Ferrer, M Ma, J Li, L Fritts, MB McChesney and CJ Miller

Citation: Retrovirology 2009 6(Suppl 3):P2

Published on: 22 October 2009
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S011-06 OA. HIV specific T cell responses and response patterns associated with viral control independent of classical non-progessor HLA class I alleles

Authors: R Zuniga, B Mothe, A Llano, J Ibarrondo, M Daniels, M Farfan, J Suarez, JJ Szinger, W Hildebrand, A Lucchetti, D Heckerman, P Goulder, BD Walker, J Sanchez, BT Korber and C Brander

Citation: Retrovirology 2009 6(Suppl 3):O3

Published on: 22 October 2009
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P01-03. Regulatory T cells and TH-17 cells counterbalance in CD4+ T cell activation in HIV-1-infected subjects progressing to immunodeficiency

Authors: KI Carvalho, FB Romano, AM Matos and EG Kallas

Citation: Retrovirology 2009 6(Suppl 3):P3

Published on: 22 October 2009
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S021-04 OA. A large-scale analysis of immunoglobulin sequences derived from plasmablasts/plasma cells in acute HIV-1 infection subjects

Authors: S Munshaw, H Liao, A Dixon, X Chen, A Nagel, K Derosa, R Parks, J Amos, JF Whitesides, DJ Marshalls, Y Yang, F Gao, GD Tomaras, MA Moody, GH Kelsoe, TC Shea…

Citation: Retrovirology 2009 6(Suppl 3):O4

Published on: 22 October 2009
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P01-04. Investigation of the sensitivity of acute-phase HIV-1 isolates to type I interferons

Authors: O Dibben, M Assa-Chapman, J Lewis, A McKnight, I Williams and P Borrow

Citation: Retrovirology 2009 6(Suppl 3):P4

Published on: 22 October 2009
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P01-05. Rapid perforin upregulation dominates the HIV-specific CD8 T cell response during acute HIV-infection

Authors: G Makedonas, I Frank, D Guidonis, MA Ostrowski, KJ Weinhold and MR Betts

Citation: Retrovirology 2009 6(Suppl 3):P5

Published on: 22 October 2009
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S021-05 OA. Broadly neutralizing anti-HIV-1 antibodies disrupt a hinge-related function of gp41 at the membrane interface

Authors: L Song, ZJ Sun, KE Coleman, MB Zwick, JS Gach, J Wang, EL Reinherz, G Wagner and M Kim

Citation: Retrovirology 2009 6(Suppl 3):O5

Published on: 22 October 2009
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P02-01. Elicitation of a humoral immune response towards non-immunogenic peptides using the transcriptional transactivator of HIV-1

Authors: A Gadzinski, E Favre, S Turbant and M Leonetti

Citation: Retrovirology 2009 6(Suppl 3):P6

Published on: 22 October 2009
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S021-06 OA. Potent and broad neutralizing antibodies from HIV-1 non-clade B infected donor reveal a new HIV-1 vaccine target

Authors: SK Phogat, L Walker, D Wagner, P Chan-Hui, M Simek, P Phung, T Wrin, J Mitcham, P Investigator, S Kaminsky, T Zamb, M Moyle, W Koff and D Burton

Citation: Retrovirology 2009 6(Suppl 3):O6

Published on: 22 October 2009
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OA011-01. Early events of human immunodeficiency virus type 1 (HIV-1) ex vivo penetration in the foreskin mimicking HIV-1 sexual transmission

Authors: Y Ganor, Z Zhou, A Schmitt, M Vacher-Lavenu, L Gibault, N Thiounn, J Tomasini, J Wolf and M Bomsel

Citation: Retrovirology 2009 6(Suppl 3):O7

Published on: 22 October 2009
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P02-02. Analysis of antigen specific degranulation potentials using IL-12 or IL-28B during HIV DNA Vaccination

Authors: M Morrow, J Yan, P Pankhong, K Harris, A Kahn, N Sardesai and D Weiner

Citation: Retrovirology 2009 6(Suppl 3):P7

Published on: 22 October 2009
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P02-03. Screening of potential adjuvants for induction of pro-IgA factors

Authors: V Buffa, K Klein, J Tregoning, A Siddiqui and R Shattock

Citation: Retrovirology 2009 6(Suppl 3):P8

Published on: 22 October 2009
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OA011-02. Defining the mechanisms of HIV entry and interactions with the female genital tract

Authors: AM Carias, S McCoombe, M McRaven, M Anderson, R Veazey and TJ Hope

Citation: Retrovirology 2009 6(Suppl 3):O8

Published on: 22 October 2009
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OA011-03. Clusterin, a natural ligand of DC-SIGN present in human semen inhibits HIV capture and transmission by dendritic cells

Authors: J Sabatte, W Faigle, A Ceballos, W Morelle, C Rodríguez, F Remes Lenicov, M Thépaut, F Fieschi, H Lortat-Jacob, J Michalski, F Arenzana-Seisdedos, J Geffner and S Amigorena

Citation: Retrovirology 2009 6(Suppl 3):O9

Published on: 22 October 2009
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P02-04. Multimeric soluble CD40 ligand efficiently enhances HIV specific cellular immune responses during DNA prime and boost with attenuated poxvirus strains

Authors: J Najera, C Gomez and M Esteban

Citation: Retrovirology 2009 6(Suppl 3):P9

Published on: 22 October 2009
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P02-05. All-trans retinoic acid during vaccination increases Ag-specific CD8 T cell homing to mucosal sites and improves recall responses to vaginal challenge

Authors: J Blattman, X Tan, J Sande, J Pufnock and P Greenberg

Citation: Retrovirology 2009 6(Suppl 3):P10

Published on: 22 October 2009
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OA011-04. Striking elevations in systemic and mucosal cytokine and chemokine levels in acute HIV-1 infection

Authors: A Stacey, P Norris, O Dibben, L Qin, M Cohen, C Gay, T Denny and P Borrow

Citation: Retrovirology 2009 6(Suppl 3):O10

Published on: 22 October 2009
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OA011-05. TLR-mediated pDC responses to HIV-1 ligands

Authors: J Chang, S Kulkarni, A Meier, RJ Lindsay, S Bazner, JD Lifson, RJ Bosch, M Carrington and M Altfeld

Citation: Retrovirology 2009 6(Suppl 3):O11

Published on: 22 October 2009
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P02-06. The adjuvancy of OX40 ligand (CD252) on an HIV-1 canarypox vaccine

Authors: J Liu, N Ngai, GW Stone, F Yue and MA Ostrowski

Citation: Retrovirology 2009 6(Suppl 3):P11

Published on: 22 October 2009
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OA01-06 LB. HIV-1 plasma RNA and risk of HIV-1 transmission

Authors: JR Lingappa, JP Hughes, D Donnel, JM Baeten, JI Mullins, MS Campbell, GE Gray, M Essex, C Farquhar, H Rees, A Wald, L Corey and C Celum

Citation: Retrovirology 2009 6(Suppl 3):O12

Published on: 22 October 2009
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P02-07. High concentrations of interleukin-15 and low concentrations of CCL5 in breast milk are associated with protection against postnatal HIV transmission

Authors: J Walter, MK Ghosh, L Kuhn, K Semrau, M Sinkala, C Kankasa, DM Thea and GM Aldrovandi

Citation: Retrovirology 2009 6(Suppl 3):P12

Published on: 22 October 2009
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OA021-01. Construction and characterization of replication competent attenuated NYVAC-based vectors as potential HIV vaccines

Authors: B Jacobs, K Kibler, S Wong, T Huynh, S Holechek, K Denzler, W Arndt, M Parrington, J Tartaglia and G Pantaleo

Citation: Retrovirology 2009 6(Suppl 3):O13

Published on: 22 October 2009
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P02-08. Enhancement of HIV-1 DNA vaccine immunogenicity by BCG-PSN, a novel adjuvant

Authors: J Sun, Y Liu, D Li, J Hou, Z Xu, W Fan, J Fu, Y Liu and Y Shao

Citation: Retrovirology 2009 6(Suppl 3):P13

Published on: 22 October 2009
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OA021-02. Replicating measles-SHIV vaccine induces long term preservation of central memory CD4 cells in the gut of vaccinated macaques challenged with SHIV

Authors: F Tangy, M Février, M Guerbois, C Combredet, V Najburg, C Ruffié, A Morris, O Schwartz and R Legrand

Citation: Retrovirology 2009 6(Suppl 3):O14

Published on: 22 October 2009
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P02-09. Dissecting the interference of endotoxins with HIV infection of primary CD4 T cell

Authors: A Krarup, P Rusert and A Trkola

Citation: Retrovirology 2009 6(Suppl 3):P14

Published on: 22 October 2009
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OA021-03. Design and development of DNA vaccines for the co-expression of micro-RNA and HIV-1 Env

Authors: AK Wheatley, MR Alexander, JG Toe, RJ Center and DF Purcell

Citation: Retrovirology 2009 6(Suppl 3):O15

Published on: 22 October 2009
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P02-10. Plant expression of chimeric Gag/gp41 virus-like particles as a mucosally-targeted subunit vaccine against HIV-1

Authors: SA Kessans, J Frater, N Matoba and T Mor

Citation: Retrovirology 2009 6(Suppl 3):P15

Published on: 22 October 2009
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OA021-04. HIV-1 gp41 envelope MPER mutation altered epitope conformation in lipid and increased sensitivity to 2F5 and 4E10 neutralizing antibodies

Authors: X Shen, M Dennison, F Gao, DC Montefiori, L Verkoczy, B Haynes, M Alam and G Tomaras

Citation: Retrovirology 2009 6(Suppl 3):O16

Published on: 22 October 2009
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P02-11. Correlate of local adjuvanticity and inflammation for experimental vaginal adjuvants in mice

Authors: M Lindqvist, N Navabi, M Jansson, Å Sjöling, C Örndal and AM Harandi

Citation: Retrovirology 2009 6(Suppl 3):P16

Published on: 22 October 2009
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OA021-05. Insertion of the HIV-1 gp41 epitopes 2F5 and 4E10 into the membrane-proximal region of the vesicular stomatitis virus glycoprotein

Authors: IC Lorenz, HT Nguyen, SK Phogat, SM Kaminsky, TJ Zamb and CL Parks

Citation: Retrovirology 2009 6(Suppl 3):O17

Published on: 22 October 2009
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P02-12. Bupivacaine, a local anaesthetic, enhances immunogenicity of a multiepitopic DNA vaccine containing HIV promiscuous CD4 T cell epitopes

Authors: DS Rosa, SP Ribeiro, EC Mairena, J Kalil and E Cunha-Neto

Citation: Retrovirology 2009 6(Suppl 3):P17

Published on: 22 October 2009
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OA02-06 LB. Recombinant modified Vaccinia virus ankara expressing HIV-1 genes activates NK subset capable of controlling HIN infection in vitro

Authors: J Cummings, V Arnold, K Yarbrough, C Didier, Y Levy, F Barré-Sinoussi and D Scott-Algara

Citation: Retrovirology 2009 6(Suppl 3):O18

Published on: 22 October 2009
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P03-01. The relationship of envelope evolution to lentiviral persistence and vaccine efficacy

Authors: JK Craigo, CJ Issel and RC Montelaro

Citation: Retrovirology 2009 6(Suppl 3):P18

Published on: 22 October 2009
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OA031-01. HIV-1 infection is characterized by early loss of CD161+ Th17 cells and gradual decline in regulatory T cells

Authors: A Prendergast, JG Prado, Y Kang, F Chen, LA Riddell, G Luzzi, P Goulder and P Klenerman

Citation: Retrovirology 2009 6(Suppl 3):O19

Published on: 22 October 2009
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P03-02. SCID-hu mice generate HIV specific human immune responses after gp96 vaccination

Authors: LE Gonzalez, N Strbo and ER Podack

Citation: Retrovirology 2009 6(Suppl 3):P19

Published on: 22 October 2009
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OA031-02. Regulatory T cells inhibit CD8 T cell proliferation in HIV-1 infection through CD39/adenosine pathway

Authors: M Nikolova, M Carriere, J Lelievre, M Muhtarova, A Bensussan and Y Lévy

Citation: Retrovirology 2009 6(Suppl 3):O20

Published on: 22 October 2009
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P03-03. Protection against SIV by anti HLA class II specific antibody in the macaque model

Authors: MJ Robinson, R Quartey-Papafio, N Almond and M Page

Citation: Retrovirology 2009 6(Suppl 3):P20

Published on: 22 October 2009
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P03-04. Increased virulence of CAEV chimeras expressing Nef and Vpx/Vpr accessory proteins in infected goats

Authors: Y Jin, G Arrode-Brusés, N Halloway, O Narayan and Y Chebloune

Citation: Retrovirology 2009 6(Suppl 3):P21

Published on: 22 October 2009
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OA031-03. Increased regulatory T cell frequency and HIV-1 specific suppression after therapeutic vaccination of HIV-infected patients on antiretroviral therapy

Authors: BC Macatangay, ME Szajnik, TL Whiteside, SA Riddler and CR Rinaldo

Citation: Retrovirology 2009 6(Suppl 3):O21

Published on: 22 October 2009
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P03-05. CD4 targeted vaccination in retroviral infection

Authors: R Pike, MJ Ploquin and G Kassiotis

Citation: Retrovirology 2009 6(Suppl 3):P22

Published on: 22 October 2009
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OA031-04. Impairment of HIV-1-specific CD8+ T cell function by soluble epithelial adhesion molecules

Authors: H Streeck, D Kwon, JS Jolin, K Trocha, M Chevalier, T Caron, K Law, A Pyo, I Toth, DE Kaufmann, SJ Rodig, BD Walker and M Altfeld

Citation: Retrovirology 2009 6(Suppl 3):O22

Published on: 22 October 2009
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OA031-05. HIV escape from natural killer cytotoxicity: Nef inhibits NKp44L expression on HIV-infected CD4+ T cells

Authors: H Fausther-Bovendo, N Sol-Foulon, O Schwartz, P Debre and V Vieillard

Citation: Retrovirology 2009 6(Suppl 3):O23

Published on: 22 October 2009
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P03-06. Preserved cellular and humoral immune responses in macaques infected with SIVmac239 and subjected to early antiretroviral therapy

Authors: B Makitalo, L Walther-Jallow, G Ozkaya Sahin, J Michaelsson, M Spangberg, R Thorstensson, E Fenyo and A Spetz

Citation: Retrovirology 2009 6(Suppl 3):P23

Published on: 22 October 2009
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OA03-06 LB. Unique stimulatory properties of myeloid dendritic cells in individuals with "elite" HIV-1 control

Authors: J Huang, L Poole, P Burke, T Cung, A Trocha, F Pereyra, L Borges, M Lichterfeld and X Yu

Citation: Retrovirology 2009 6(Suppl 3):O24

Published on: 22 October 2009
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P03-07. Autologous neutralizing antibodies that select viral escape variants emerge late after SIV infection of rhesus monkeys

Authors: WW Yeh, I Rahman, P Hraber, A Giri, D Nevidomskyte, RT Coffey, M Asmal, S Miljkovic, JB Whitney, BF Keele, GM Shaw, BT Korber, MS Seaman and NL Letvin

Citation: Retrovirology 2009 6(Suppl 3):P24

Published on: 22 October 2009
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OA04-01. Safety and immunogenicity of LIPO-5, a HIV-1 lipopeptide vaccine: results of ANRS VAC18, a phase 2, randomized, double-blind, placebo-controlled trial

Authors: D Salmon-Céron, C Durier, C Desaint, Cuzin, M Surenaud, Y Hénin, J Lelièvre, B Bonnet, G Pialoux, I Poizot-Martin, N Ben Hamouda, A Jackson, C Flys, C Guérin, J Aboulker, J Choppin…

Citation: Retrovirology 2009 6(Suppl 3):O25

Published on: 22 October 2009
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P03-08. Protection against SIVmac239 challenge in a rhesus macaque model conferred by a doxycycline dependent attenuated SIVmac239

Authors: M Page, N Berry, M Robinson, R Quartey-Papafio, W Elsley, H Tudor, A Das, W Kleibeuker, B Klaver, B Li, M Manoussaka, R Stebbings, M Cranage, B Berkhout and N Almond

Citation: Retrovirology 2009 6(Suppl 3):P25

Published on: 22 October 2009
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