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682 result(s) for 'endogenous' within Retrovirology

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  1. Here, we report the complete genome of the first extant prosimian FV (PSFV) isolated from a lorisiforme galago (PSFVgal), and a novel partial endogenous viral element with high sequence similarity to ... . We als...

    Authors: Aris Katzourakis, Pakorn Aiewsakun, Hongwei Jia, Nathan D Wolfe, Matthew LeBreton, Anne D Yoder and William M Switzer
    Citation: Retrovirology 2014 11:61
    Content type: Research Published on:

  2. The human genome contains multiple copies of retrovirus genomes known as endogenous retroviruses (ERVs) that have entered the ... , gamma-, or spuma- retrovirus groups. Endogenous delta- and lenti- viruses are no...

    Authors: Antoinette C van der Kuyl
    Citation: Retrovirology 2012 9:6
    Content type: Review Published on:

  4. Real-time PCR analysis of 110 PCa (Gleason scores >4) and 40 benign and normal prostate tissues identified six positive samples (5 PCa and 1 non-PCa). No statistical link was observed between the presence of p...

    Authors: Toshie Sakuma, Stéphane Hué, Karen A Squillace, Jason M Tonne, Patrick R Blackburn, Seiga Ohmine, Tayaramma Thatava, Greg J Towers and Yasuhiro Ikeda
    Citation: Retrovirology 2011 8:23
    Content type: Research Published on:

  5. The Tax protein encoded by Human T-lymphotropic virus type 1 (HTLV-1) is a powerful activator of the NF-κB pathway, a property critical for HTLV-1-induced immortalization of CD4+ T lymphocytes. Tax permanently st...

    Authors: Amandine Bonnet, Voahangy Randrianarison-Huetz, Patrycja Nzounza, Martine Nedelec, Maxime Chazal, Laetitia Waast, Sabrina Pene, Ali Bazarbachi, Renaud Mahieux, Laurence Bénit and Claudine Pique
    Citation: Retrovirology 2012 9:77
    Content type: Research Published on:

  6. Human immunodeficiency virus type 1 (HIV-1) has evolved a complex strategy to overcome the immune barriers it encounters throughout an organism thanks to its viral infectivity factor (Vif), a key protein for H...

    Authors: María-Soledad Valera, Laura de Armas-Rillo, Jonathan Barroso-González, Serena Ziglio, Julien Batisse, Noé Dubois, Sara Marrero-Hernández, Sophie Borel, Laura García-Expósito, Martine Biard-Piechaczyk, Jean-Christophe Paillart and Agustín Valenzuela-Fernández
    Citation: Retrovirology 2015 12:53
    Content type: Research Published on:

  7. O18 Reprogramming initiates mobilization of endogenous mutagenic LINE-1, Alu and SVA retrotransposons in human induced pluripotent stem cells with consequences for host gene expression

    Authors: Irena Zurnic, Sylvia Hütter, Ute Lehmann, Nicole Stanke, Juliane Reh, Tobias Kern, Fabian Lindel, Gesche Gerresheim, Martin Hamann, Erik Müllers, Paul Lesbats, Peter Cherepanov, Erik Serrao, Alan Engelman, Dirk Lindemann, Claire Da Silva Santos…
    Citation: Retrovirology 2016 13(Suppl 1):68
    Content type: Meeting abstracts Published on:

    This article is part of a Supplement: Volume 13 Supplement 1

  8. In this study, we first demonstrate that endogenous hBST-2 is predominantly expressed on the ... encoded Vpu has the potential to down-regulate endogenous hBST-2 from the surface of HIV-...

    Authors: Kei Sato, Seiji P Yamamoto, Naoko Misawa, Takeshi Yoshida, Takayuki Miyazawa and Yoshio Koyanagi
    Citation: Retrovirology 2009 6:53
    Content type: Short report Published on:

  9. In this study, we have demonstrated that overexpressed as well as endogenous APOBEC3G were incorporated into HTLV-1 virions...

    Authors: Amane Sasada, Akifumi Takaori-Kondo, Kotaro Shirakawa, Masayuki Kobayashi, Aierkin Abudu, Masakatsu Hishizawa, Kazunori Imada, Yuetsu Tanaka and Takashi Uchiyama
    Citation: Retrovirology 2005 2:32
    Content type: Research Published on:

  10. Human T-cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia (ATL). Treatment options are limited and prophylactic agents are not available. We have previously demonstrated an essential role for CR...

    Authors: Hei-Man Vincent Tang, Wei-Wei Gao, Ching-Ping Chan, Yeung-Tung Siu, Chi-Ming Wong, Kin-Hang Kok, Yick-Pang Ching, Hiroshi Takemori and Dong-Yan Jin
    Citation: Retrovirology 2013 10:40
    Content type: Research Published on:

  11. The human T-cell leukemia virus type I (HTLV-I) basic leucine-zipper factor (HBZ) has previously been shown to modulate transcriptional activity of Jun family members. The presence of a novel isoform of HBZ, t...

    Authors: Patrick Hivin, Jihane Basbous, Frédéric Raymond, Daniel Henaff, Charlotte Arpin-André, Véronique Robert-Hebmann, Benoit Barbeau and Jean-Michel Mesnard
    Citation: Retrovirology 2007 4:14
    Content type: Research Published on:

  12. Bone marrow stromal cell antigen 2 (BST-2) is a cellular factor that restricts the egress of viruses such as human immunodeficiency virus (HIV-1) from the surface of infected cells, preventing infection of new...

    Authors: Philip H Jones, Harshini V Mehta, Martina Maric, Richard J Roller and Chioma M Okeoma
    Citation: Retrovirology 2012 9:10
    Content type: Research Published on:

  13. Here, we report that SAMHD1 significantly blocked single-cycle and replication-competent HIV-1 infection of DCs by decreasing the intracellular dNTP pool and thereby limiting the accumulation of HIV-1 late revers...

    Authors: Corine St Gelais, Suresh de Silva, Sarah M Amie, Christopher M Coleman, Heather Hoy, Joseph A Hollenbaugh, Baek Kim and Li Wu
    Citation: Retrovirology 2012 9:105
    Content type: Research Published on:

  14. Xenotropic murine leukaemia viruses (MLV-X) are endogenous gammaretroviruses that infect cells from many species,...

    Authors: Stéphane Hué, Eleanor R Gray, Astrid Gall, Aris Katzourakis, Choon Ping Tan, Charlotte J Houldcroft, Stuart McLaren, Deenan Pillay, Andrew Futreal, Jeremy A Garson, Oliver G Pybus, Paul Kellam and Greg J Towers
    Citation: Retrovirology 2010 7:111
    Content type: Research Published on:

  15. In 2006, a novel gammaretrovirus, XMRV (xenotropic murine leukemia virus-related virus), was discovered in some prostate tumors. A more recent study indicated that this infectious retrovirus can be detected in 67...

    Authors: Brendan Oakes, Albert K Tai, Oya Cingöz, Madeleine H Henefield, Susan Levine, John M Coffin and Brigitte T Huber
    Citation: Retrovirology 2010 7:109
    Content type: Research Published on:

  16. Here we present evidence that re-expression of a LEDGF/p75 mutant lacking the PWWP domain (ΔPWWP) rescued HIV-1 infection in cells verified to express background levels of endogenous LEDGF/p75 that do not support...

    Authors: Paulina Astiazaran, Murilo TD Bueno, Elisa Morales, Jeffrey R Kugelman, Jose A Garcia-Rivera and Manuel Llano
    Citation: Retrovirology 2011 8:27
    Content type: Research Published on:

  17. The results revealed that: (1) EloB (and EloC) positively affected the recruitment of CBF-β to Vif. Both knockdown of endogenous EloB and over-expression of its mutant...Escherichia coli. (4) The over-expression ...

    Authors: Xiaodan Wang, Xiaoying Wang, Haihong Zhang, Mingyu Lv, Tao Zuo, Hui Wu, Jiawen Wang, Donglai Liu, Chu Wang, Jingyao Zhang, Xu Li, Jiaxin Wu, Bin Yu, Wei Kong and Xianghui Yu
    Citation: Retrovirology 2013 10:94
    Content type: Research Published on:

  18. The cellular transmembrane protein CD317/BST-2/HM1.24/Tetherin restricts HIV-1 infection by physically tethering mature virions to the surface of infected cells. HIV-1 counteracts this restriction by expressin...

    Authors: Hanna-Mari Tervo, Stefanie Homann, Ina Ambiel, Joëlle V Fritz, Oliver T Fackler and Oliver T Keppler
    Citation: Retrovirology 2011 8:9
    Content type: Research Published on:

  21. The anti-viral function of RNA silencing was first discovered in plants as a natural manifestation of the artificial 'co-suppression', which refers to the extinction of endogenous gene induced by homologous trans...

    Authors: Anne Saumet and Charles-Henri Lecellier
    Citation: Retrovirology 2006 3:3
    Content type: Review Published on:

  22. We and others have recently demonstrated that the human retrovirus HTLV-I was producing a spliced antisense transcript, which led to the synthesis of the HBZ protein. The objective of the present study was to ...

    Authors: Sébastien Landry, Marilène Halin, Sylvain Lefort, Brigitte Audet, Catherine Vaquero, Jean-Michel Mesnard and Benoit Barbeau
    Citation: Retrovirology 2007 4:71
    Content type: Research Published on:

  23. The role of mouse mammary tumor virus (MMTV) as a causative agent in human breast carcinogenesis has recently been the subject of renewed interest. The proposed model is based on the detection of MMTV sequence...

    Authors: Stanislav Indik, Walter H Günzburg, Pavel Kulich, Brian Salmons and Francoise Rouault
    Citation: Retrovirology 2007 4:73
    Content type: Research Published on:

  24. The Human Immunodeficiency virus type 1 (HIV-1) Vpu protein enhances virus release from infected cells and induces proteasomal degradation of CD4. Recent work identified BST-2/CD317 as a host factor that inhib...

    Authors: Amy J Andrew, Eri Miyagi, Sandra Kao and Klaus Strebel
    Citation: Retrovirology 2009 6:80
    Content type: Research Published on:

  25. In response to viral infections, interferons induce the transcription of several hundred genes in mammalian cells. Specific antiviral functions, however, have only been attributed to a few of them. 90K/LGALS3BP h...

    Authors: Veronika Lodermeyer, Kristina Suhr, Nicola Schrott, Christian Kolbe, Christina M Stürzel, Daniela Krnavek, Jan Münch, Christian Dietz, Tanja Waldmann, Frank Kirchhoff and Christine Goffinet
    Citation: Retrovirology 2013 10:111
    Content type: Research Published on:

  26. The majority of emerging infectious diseases in humans are of animal origin, and many of them are caused by neuropathogenic viruses. Many cases of neurological disease and encephalitis in livestock remain etio...

    Authors: Melanie M. Hierweger, Michel C. Koch, Ronja V. Kauer, Zoltán Bagó, Anna Oevermann, Giuseppe Bertoni and Torsten Seuberlich
    Citation: Retrovirology 2021 18:40
    Content type: Research Published on:

    The Correction to this article has been published in Retrovirology 2022 19:5

  27. Here, we have identified transforming growth factor-β-activated kinase 1 (TAK1) as the important upstream signaling molecule that Vpr associates with in order to activate NF-κB and AP-1 signaling. HIV-1 virion-as...

    Authors: Ruikang Liu, Yongquan Lin, Rui Jia, Yunqi Geng, Chen Liang, Juan Tan and Wentao Qiao
    Citation: Retrovirology 2014 11:45
    Content type: Research Published on:

  35. Consistent with previous studies, HXB2-Met(e) were infectious and maintained this PBS following short-term in vitro culture in SupT1 cells. In contrast, transfection of HBX2-Met(i) produced reduced amounts of vir...

    Authors: Uros V Djekic and Casey D Morrow
    Citation: Retrovirology 2007 4:10
    Content type: Research Published on:

  37. Once integrated in the genome of infected cells, HIV-1 provirus is transcribed by the cellular transcription machinery. This process is regulated by both viral and cellular factors, which are necessary for an ...

    Authors: María José Lista, Anne-Caroline Jousset, Mingpan Cheng, Violaine Saint-André, Elouan Perrot, Melissa Rodrigues, Carmelo Di Primo, Danielle Gadelle, Elenia Toccafondi, Emmanuel Segeral, Clarisse Berlioz-Torrent, Stéphane Emiliani, Jean-Louis Mergny and Marc Lavigne
    Citation: Retrovirology 2023 20:10
    Content type: Review Published on:

    The Correction to this article has been published in Retrovirology 2023 20:12

  39. NL4.3 viruses were produced from cells cultured in the presence of PKA inhibitors H89 (H89-NL4.3) or Myr-PKI (PKI-NL4.3) and analyzed for viral replication. Despite being mature and normally assembled, and contai...

    Authors: Charline Giroud, Nathalie Chazal, Bernard Gay, Patrick Eldin, Sonia Brun and Laurence Briant
    Citation: Retrovirology 2013 10:157
    Content type: Research Published on:

  42. HIV and SIV defeat antiviral proteins by usurping Cullin-RING E3 ubiquitin ligases (CRLs) and likely influence other cellular processes through these as well. HIV-2 viral protein X (Vpx) engages the cullin4-co...

    Authors: Michael D Nekorchuk, Hamayun J Sharifi, Andrea KM Furuya, Robert Jellinger and Carlos MC de Noronha
    Citation: Retrovirology 2013 10:138
    Content type: Research Published on:

  43. To seek a possible mechanism that could explain how Nullbasic inhibits Rev activity, we used a proteomics approach to identify host cellular proteins that interact with Nullbasic. Forty-six Nullbasic-binding prot...

    Authors: Min-Hsuan Lin, Haran Sivakumaran, Alun Jones, Dongsheng Li, Callista Harper, Ting Wei, Hongping Jin, Lina Rustanti, Frederic A Meunier, Kirsten Spann and David Harrich
    Citation: Retrovirology 2014 11:121
    Content type: Research Published on:

  44. Despite the large amount of data available on the molecular mechanisms that regulate HIV-1 transcription, crucial information is still lacking about the interplay between chromatin conformation and the events ...

    Authors: Chiara Vardabasso, Lara Manganaro, Marina Lusic, Alessandro Marcello and Mauro Giacca
    Citation: Retrovirology 2008 5:8
    Content type: Research Published on:

  45. The 1st International Workshop on Xenotropic Murine Leukemia Virus-Related Retrovirus (XMRV), co-sponsored by the National Institutes of Health, The Department of Health and Human Services and Abbott Diagnostics,...

    Authors: Jonathan P Stoye, Robert H Silverman, Charles A Boucher and Stuart FJ Le Grice
    Citation: Retrovirology 2010 7:113
    Content type: Review Published on:

  46. The deoxynucleotide-triphosphate (dNTP) hydrolase sterile alpha motif domain and HD domain 1 (SAMHD1) is a nuclear protein that inhibits HIV-1 infection in myeloid cells as well as quiescent CD4 T-cells, by de...

    Authors: Torsten Schaller, Darja Pollpeter, Luis Apolonia, Caroline Goujon and Michael H Malim
    Citation: Retrovirology 2014 11:29
    Content type: Research Published on:

  47. As previously reported, ectopic expression of Glut-1 but not Glut-3 resulted in significantly augmented binding of tagged proteins harboring the receptor binding domains of either HTLV-1 or HTLV-2 envelope gly...

    Authors: Sandrina Kinet, Louise Swainson, Madakasira Lavanya, Cedric Mongellaz, Amélie Montel-Hagen, Marco Craveiro, Nicolas Manel, Jean-Luc Battini, Marc Sitbon and Naomi Taylor
    Citation: Retrovirology 2007 4:31
    Content type: Research Published on:

  49. Degradation of p65/RelA has been involved in both the inhibition of NF-κB-dependent activity and the onset of apoptosis. However, the mechanisms of NF-κB degradation are unclear and can vary depending on the c...

    Authors: Mayte Coiras, María Rosa López-Huertas, Elena Mateos and José Alcamí
    Citation: Retrovirology 2008 5:109
    Content type: Research Published on:

  50. The discovery of novel anti-viral restriction factors illuminates unknown aspects of innate sensing and immunity. We identified RNA-associated Early-stage Anti-viral Factor (REAF) using a whole genome siRNA sc...

    Authors: Kelly M Marno, Babatunji W Ogunkolade, Corinna Pade, Nidia MM Oliveira, Eithne O’Sullivan and Áine McKnight
    Citation: Retrovirology 2014 11:3
    Content type: Research Published on:
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