Skip to main content

Articles

Page 91 of 93

  1. The persistence of latent HIV-1 reservoirs is the principal barrier preventing the eradication of HIV-1 infection in patients by current antiretroviral therapy. It is thus crucial to understand the molecular m...

    Authors: Sandie Munier, Delphine Delcroix-Genête, Laëtitia Carthagéna, Audrey Gumez and Uriel Hazan
    Citation: Retrovirology 2005 2:73
  2. Every year the Cancer Research Institute from University of California at Irvine organizes the West Coast Retrovirus Meeting where participants have a chance to discuss the latest progress in understanding the...

    Authors: Sheila M Barry, Marta Melar, Philippe Gallay and Thomas J Hope
    Citation: Retrovirology 2005 2:72
  3. Human T-cell leukemia virus type 1 and type 2 are related human retroviruses. HTLV-1 is the etiological agent of the Adult T-cell Leukemia/Lymphoma and of the Tropical Spastic Paraparesis/HTLV-1 Associated Mye...

    Authors: Sébastien A Chevalier, Laurent Meertens, Sara Calattini, Antoine Gessain, Lars Kiemer and Renaud Mahieux
    Citation: Retrovirology 2005 2:70
  4. Human immunodeficiency virus type 1 (HIV-1) Tat transactivation is an essential step in the viral life cycle. Over the past several years, it has become widely accepted that Tat exerts its transcriptional effe...

    Authors: John Brady and Fatah Kashanchi
    Citation: Retrovirology 2005 2:69
  5. Given the high prevalence of mother to child infection, the development of a better understanding of African subtype C HIV-1 transmission and natural evolution is of significant importance. In this study, we g...

    Authors: Hong Zhang, Federico Hoffmann, Jun He, Xiang He, Chipepo Kankasa, Ruth Ruprecht, John T West, Guillermo Orti and Charles Wood
    Citation: Retrovirology 2005 2:67
  6. We have examined the kinetics of processing of the HIV-1 Gag-Pro-Pol precursor in an in vitro assay with mature protease added in trans. The processing sites were cleaved at different rates to produce distinct...

    Authors: Steve C Pettit, Jeffrey N Lindquist, Andrew H Kaplan and Ronald Swanstrom
    Citation: Retrovirology 2005 2:66
  7. Increasing evidence indicates that RNA interference (RNAi) may be used to provide antiviral immunity in mammalian cells. Human micro (mi)RNAs can inhibit the replication of a primate virus, whereas a virally-e...

    Authors: Anne Gatignol, Sébastien Lainé and Guerline Clerzius
    Citation: Retrovirology 2005 2:65
  8. Human T-cell leukemia virus type I (HTLV-I) causes adult T-cell leukemia (ATL) after a long latent period. Among accessory genes encoded by HTLV-I, the tax gene is thought to play a central role in oncogenesis. H...

    Authors: Yuko Taniguchi, Kisato Nosaka, Jun-ichirou Yasunaga, Michiyuki Maeda, Nancy Mueller, Akihiko Okayama and Masao Matsuoka
    Citation: Retrovirology 2005 2:64
  9. HIV-1 and all retroviruses are related to retroelements of simpler organisms such as the yeast Ty elements. Recent work has suggested that the yeast retroelement Ty1 replicates via an unexpected RNA lariat int...

    Authors: Ying Ye, Jessica De Leon, Noriko Yokoyama, Yathi Naidu and David Camerini
    Citation: Retrovirology 2005 2:63
  10. In addition to mediating the integration process, HIV-1 integrase (IN) has also been implicated in different steps during viral life cycle including reverse transcription and viral DNA nuclear import. Although...

    Authors: Zhujun Ao, Keith R Fowke, Éric A Cohen and Xiaojian Yao
    Citation: Retrovirology 2005 2:62
  11. Dicistronic MLV-based retroviral vectors, in which two IRESes independently initiate the translation of two proteins from a single RNA, have been shown to direct co-expression of proteins in several cell cultu...

    Authors: Edmund A Derrington, Marcelo López-Lastra and Jean-Luc Darlix
    Citation: Retrovirology 2005 2:60
  12. Infection by jaagsiekte sheep retrovirus (JSRV) and by enzootic nasal tumor virus (ENTV) depends on cell-surface expression of the virus entry receptor, hyaluronidase 2 (Hyal2). Human Hyal2 binds the envelope ...

    Authors: Fuh-Mei Duh, Clarissa Dirks, Michael I Lerman and A Dusty Miller
    Citation: Retrovirology 2005 2:59
  13. A series of amino acid substitutions (M239F, M239G, P240F, V241G) were placed in the p10-CA protease cleavage site (VVAM*PVVI) to change the rate of cleavage of the junction. The effects of these substitutions...

    Authors: Marcy L Vana, Aiping Chen, Peter Boross, Irene Weber, Dalbinder Colman, Eric Barklis and Jonathan Leis
    Citation: Retrovirology 2005 2:58
  14. The human HERV-W multicopy family includes a unique proviral locus, termed ERVWE1, whose full-length envelope ORF was preserved through evolution by the action of a selective pressure. The encoded Env protein ...

    Authors: Bertrand Bonnaud, Jean Beliaeff, Olivier Bouton, Guy Oriol, Laurent Duret and François Mallet
    Citation: Retrovirology 2005 2:57
  15. A recent publication in Lancet by Dr. David Margolis and colleagues raised the prospect that HIV infection may be curable. In this pilot study, which received much attention from the press, Dr. Margolis'group fou...

    Authors: Stephen M Smith
    Citation: Retrovirology 2005 2:56
  16. Lentiviral vectors have shown immense promise as vehicles for gene delivery to non-dividing cells particularly to cells of the central nervous system (CNS). Improvements in the biosafety of viral vectors are p...

    Authors: Padraig M Strappe, David W Hampton, Douglas Brown, Begona Cachon-Gonzalez, Maeve Caldwell, James W Fawcett and Andrew ML Lever
    Citation: Retrovirology 2005 2:55
  17. The Tax oncoprotein of human T-cell leukemia virus type 1 (HTLV-1) is leukemogenic in transgenic mice and induces permanent T-cell growth in vitro. It is found in active CDK holoenzyme complexes from adult T-cell...

    Authors: Kirsten Fraedrich, Birthe Müller and Ralph Grassmann
    Citation: Retrovirology 2005 2:54
  18. The retroviral phenomenon of superinfection resistance (SIR) defines an interference mechanism that is established after primary infection, preventing the infected cell from being superinfected by a similar ty...

    Authors: Micha Nethe, Ben Berkhout and Antoinette C van der Kuyl
    Citation: Retrovirology 2005 2:52
  19. Endogenous retroviral sequences (ERVs) are integral parts of most eukaryotic genomes and vastly outnumber exogenous retroviruses (XRVs). ERVs with a relatively complete structure were retrieved from the geneti...

    Authors: Patric Jern, Göran O Sperber and Jonas Blomberg
    Citation: Retrovirology 2005 2:50
  20. There is evidence suggesting that actin binding to HIV-1 encoded proteins, or even actin dynamics themselves, might play a key role in virus budding and/or release from the infected cell. A crucial step in the...

    Authors: Gilles Audoly, Michel R Popoff and Pablo Gluschankof
    Citation: Retrovirology 2005 2:48
  21. HIV-1 Tat protein recruits human positive transcription elongation factor P-TEFb, consisting of CDK9 and cyclin T1, to HIV-1 transactivation response (TAR) RNA. CDK9 is maintained in dephosphorylated state by ...

    Authors: Tatyana Ammosova, Kareem Washington, Zufan Debebe, John Brady and Sergei Nekhai
    Citation: Retrovirology 2005 2:47
  22. Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic agent of adult T-cell leukemia (ATL), whereas HTLV type 2 (HTLV-2), is not associated with ATL or any other leukemia. HTLV-1 encodes the transformin...

    Authors: Chikako Tsubata, Masaya Higuchi, Masahiko Takahashi, Masayasu Oie, Yuetsu Tanaka, Fumitake Gejyo and Masahiro Fujii
    Citation: Retrovirology 2005 2:46
  23. The HTLV-1 Tax oncoprotein rapidly induces cytogenetic damage which can be measured by a significant increase in the number of micronuclei (MN) in cells. Tax is thought to have both aneuploidogenic and clastog...

    Authors: Franca Majone, Roberto Luisetto, Daniela Zamboni, Yoichi Iwanaga and Kuan-Teh Jeang
    Citation: Retrovirology 2005 2:45
  24. We determined the relative ratios of Gag and Pol molecules in highly purified virions of spumaretroviruses or foamy viruses (FVs) using monoclonal antibodies and bacterially expressed reference proteins. We fo...

    Authors: Marc Cartellieri, Wolfram Rudolph, Ottmar Herchenröder, Dirk Lindemann and Axel Rethwilm
    Citation: Retrovirology 2005 2:44
  25. The positive transcription elongation factor b (P-TEFb) composed by CDK9/CyclinT1 subunits is a dedicated co-factor of HIV transcriptional transactivator Tat protein. Transcription driven by the long terminal ...

    Authors: Alessandro Fraldi, Francesca Varrone, Giuliana Napolitano, Annemieke A Michels, Barbara Majello, Olivier Bensaude and Luigi Lania
    Citation: Retrovirology 2005 2:42
  26. The actual relationship between viral variability and HIV disease progression and/or non-progression can only be extrapolated through epidemiologically-linked HIV-infected cohorts. The rarity of such cohorts a...

    Authors: Meriet Mikhail, Bin Wang, Philippe Lemey, Brenda Beckthold, Anne-Mieke Vandamme, M John Gill and Nitin K Saksena
    Citation: Retrovirology 2005 2:41
  27. GBV-C virus infection has been linked to improved clinical outcome in HIV-1 co-infected individuals. The epidemiology of GBV-C has, thus far, been limited to the gay male, HIV+ population. Here we describe the pr...

    Authors: Stephen M Smith, Michael J Donio, Mahender Singh, James P Fallon, Lavanya Jitendranath, Natalia Chkrebtii, Jihad Slim, Diana Finkel and George Perez
    Citation: Retrovirology 2005 2:38
  28. APOBEC3G is a cellular cytidine deaminase that was recently identified as the Vif-sensitive antiviral host factor responsible for the restriction of vif-defective HIV-1 in primary human cells and certain non-perm...

    Authors: Klaus Strebel
    Citation: Retrovirology 2005 2:37
  29. The reverse transcriptase (RT) enzyme of human immunodeficiency virus type 1 (HIV-1) plays a crucial role in the life cycle of the virus by converting the single stranded RNA genome into double stranded DNA th...

    Authors: Vasudha Sundaravaradan, Tobias Hahn and Nafees Ahmad
    Citation: Retrovirology 2005 2:36
  30. Apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like 3G (APOBEC3G) is a host cellular protein with a broad antiviral activity. It inhibits infectivitiy of a wide variety of retroviruses by deaminati...

    Authors: Amane Sasada, Akifumi Takaori-Kondo, Kotaro Shirakawa, Masayuki Kobayashi, Aierkin Abudu, Masakatsu Hishizawa, Kazunori Imada, Yuetsu Tanaka and Takashi Uchiyama
    Citation: Retrovirology 2005 2:32
  31. Retroviral integration is central to viral persistence and pathogenesis, cancer as well as host genome evolution. However, it is unclear why integration appears essential for retrovirus production, especially ...

    Authors: Olivier Delelis, Caroline Petit, Herve Leh, Gladys Mbemba, Jean-François Mouscadet and Pierre Sonigo
    Citation: Retrovirology 2005 2:31

Annual Journal Metrics