Skip to main content
Figure 5 | Retrovirology

Figure 5

From: Modulation of human endogenous retrovirus (HERV) transcription during persistent and de novo HIV-1 infection

Figure 5

Transcriptional activity of HERV-K (HML-2) proviral loci in de novo and persistently infected cells. The Y-axis shows the x-fold relative expression of HERV-K (HML-2) gag transcripts in infected cells referred to uninfected cells. Relative transcription was quantified according to [85] and normalized to RPII transcript levels. HERV-K (HML-2) transcripts were amplified using gag-specific primers, cloned, sequenced and assigned to proviral loci as described previously [58]. For each HERV-K (HML-2) locus the relative cloning frequency of cDNA is shown as percentage of the total HERV-K (HML-2) transcription level determined by qRT-PCR.

Back to article page

Retrovirology

ISSN: 1742-4690

Contact us