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Figure 5 | Retrovirology

Figure 5

From: Diminished transmission of drug resistant HIV-1 variants with reduced replication capacity in a human transmission model

Figure 5

Lower infection of LCs and DCs by M184 variants. HIV infection of LCs (A) or DCs (B) by a panel of HIV-1 drug resistance variants (M184V, −I, −T and K103N) was measured after six days. All infections were started with virus equivalent to 17.5 ng (open bars) and 100 ng (filled bars) p24. Cells were stained with antibodies against CD1a as marker of LCs and intracellular p24 for HIV infection and analyzed by flow cytometry. The percentage p24 positive LCs (A) or DCs (B) is depicted. Abbreviation: n.c.: no infection control.

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Retrovirology

ISSN: 1742-4690

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