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Service outcome of antiretroviral Post-Exposure Prophylaxis (PEP) for occupational HIV exposure among health care personnel

  • 1,
  • 1,
  • 1,
  • 1,
  • 1Email author,
  • 1,
  • 1,
  • 1,
  • 1 and
  • 1
Retrovirology20107 (Suppl 1) :P75

https://doi.org/10.1186/1742-4690-7-S1-P75

  • Published:

Keywords

  • Occupational Exposure
  • Infection Risk
  • Health Care Personnel
  • Service Outcome
  • Civil Hospital

Background

This study aims to assessment of the outcome of Post Exposure Prophylaxis (PEP) Service at Centre of Excellence (CoE), ART Centre, B. J. Medical College, Civil Hospital, Ahmedabad, Gujarat, India among Health Care Personnel (HCP).

Methods

Potentially exposed to infectious materials HCPs of the institute were studied. Exposed HCP were enrolled and followed up as per Management of Occupational Exposure including PEP for HIV by National AIDS Control Organization (NACO) India guidelines.

Results

Total of 43 exposed HCP (18 male and 25 female with male to female ratio 0.72: 1) during October 2008 to October 2009 were studied, Table 1.

Table 1

Parameter

No. Of Cases (n = 43)

Universal Precaution Workshop (UPW) for HCP

 

January 2008 -- December 2008

2

January 2009 -- October 2009

9

Enrolment of HCP for PEP at CoE

 

October 2008 -- May 2009

19(44.18%)

June 2009 -- October 2009

24(55.81%)

HCP Category Enrolled for PEP at CoE

 

Medics

19(44.18%)

Paramedics

21(48.8%)

Servants

3(7%)

HIV Status of the HCP for PEP enrolment

 

October 2008--May 2009(n = 19)

Reactive

0

 

Non -- Reactive

7(36.8%)

 

Unknown

12(63.15%)

June 2009--October 2009(n = 24)

Reactive

0

 

Non -- Reactive

16(66.66%)

 

Unknown

3(12.5%)

Type of Exposure

 

Mild

21(48.8%)

Moderate

18(41.9%)

Severe

4(9.3%)

Reporting Timeline of exposed HCP to the CoE

 

<2 hours

27(62.8%)

2 -- 24 hours

9(20.9%)

24 -- 72 hours

5(11.6%)

>72 hours

2(4.7%)

HIV Status of the source

 

Reactive

22(51.2%)

Unknown

21(48.8%)

PEP Regimen Prescribed

 

Basic (Zidovudine+Lamivudine)

30(69.76%)

Expanded (Zidovudine+Lamivudine+Lopinavir/Ritonavir)

12(27.90%)

Expanded (Zidovudine+Lamivudine+Indinavir)

1(2.32%)

HIV Status of exposed HCP post PEP at 6 months (n = 18)

 

Reactive

0

Non -- Reactive

3(16.66%)

Unknown

15(83.33%)

HCP Not Completed 6 Months (n = 43)

25(58.13%)

Discussion

Those tested for HIV were all Non -- Reactive; shows the effectiveness of PEP services. We are finding obstacles on follow up tracking like "I am much aware about the risk, stigma of HIV Positivity, negligence for follow up and confidentiality issues at the workplace etc." that prevent the HCP for PEP and increase the risk of transmission. Practice and regular sensitization with UPW has increased the awareness among HCP for reducing HIV infection risk and transmission and prevention through PEP.

Authors’ Affiliations

(1)
ART center B J Medical College, Ahmedabad, India

Copyright

© Shah et al; licensee BioMed Central Ltd. 2010

This article is published under license to BioMed Central Ltd.

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