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Table 5 Host restriction factors that inhibit replication of gammaretroviruses.

From: The mouse "xenotropic" gammaretroviruses and their XPR1 receptor

  Restriction*
Restriction Factor X-MLV P-MLV XMRV E-MLV
Xpr1 + + + -
Entry: glycosylation + - - +
Lvif + + ? -
ERV interference ? + (Rmcf genes) ? +(Fv4)
Fv1 + + + +
Apobec3 -? +? + +
Tetherin/BST2 ? ? + +
  1. *+, infectious virus known to be inhibited; determination of Apobec3 restriction of X/P-MLVs based on mutational patterns found in ERVs [25].