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Erratum to: Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors

The original article was published in Retrovirology 2009 6:25

Abstract

Correction to Erik Serrao, Srinivas Odde, Kavya Ramkumar and Nouri Neamati: Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors. Retrovirology 2009, 6:25. Since the recent publication of our article (Neamati, Retrovirology 2009, 6:25), we have noticed an error which we would like to correct and we would like to apologise to the readers for this mistake.

Correction

The structure of BMS-707035 has not been publicly released. In Figure one on page 2 and a discussion on page 5 of our published paper [1], we mistakenly assigned a structure and activity data to BMS-707035. The structure and activity data that we mentioned actually belong to a different compound from the same group. The resistance pattern of BMS-707035 is "overlapping" rather than identical to raltegravir. Please see the following references [2, 3] for a detailed description of their development of pyrimidine carboxamides.

References

  1. 1.

    Serrao Erik, Odde Srinivas, Ramkumar Kavya, Neamati Nouri: Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors. Retrovirology. 2009, 6: 25-10.1186/1742-4690-6-25.

  2. 2.

    Dicker IB, Samanta HK, Li Z, Hong Y, Tian Y, Banville J, Remillard RR, Walker MA, Langley DR, Krystal M: Changes to the HIV long terminal repeat and to HIV integrase differentially impact HIV integrase assembly, activity, and the binding of strand transfer inhibitors. J Biol Chem. 2007, 282 (43): 31186-96. 10.1074/jbc.M704935200.

  3. 3.

    Dicker IB, Terry B, Lin Z, Li Z, Bollini S, Samanta HK, Gali V, Walker MA, Krystal MR: Biochemical analysis of HIV-1 integrase variants resistant to strand transfer inhibitors. J Biol Chem. 2008, 283 (35): 23599-609. 10.1074/jbc.M804213200.

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Author information

Correspondence to Nouri Neamati.

Additional information

The online version of the original article can be found at 10.1186/1742-4690-6-25

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Serrao, E., Odde, S., Ramkumar, K. et al. Erratum to: Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors. Retrovirology 6, 33 (2009) doi:10.1186/1742-4690-6-33

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