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Figure 8 | Retrovirology

Figure 8

From: Inhibition of HIV-1 integrase nuclear import and replication by a peptide bearing integrase putative nuclear localization signal

Figure 8

NLS-IN-Pen inhibits nuclear import of viral DNA. H9 lymphocytes were infected by wild-type HIV-1 at a MOI of 1; and (A) following infection, the nuclei fraction was isolated from half of the cells, and the amount of viral DNA was estimated using real time PCR method. (B) The amount of 2LTR circles was estimated using real time PCR method. All other experimental details are as described in Methods. Error bars represent standard deviation which is about +/-5%

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