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Figure 1 | Retrovirology

Figure 1

From: Downregulation of CD94/NKG2A inhibitory receptors on CD8+T cells in HIV infection is more pronounced in subjects with detected viral load than in their aviraemic counterparts

Figure 1

CD94/NKG2A expression in CD8+ T lymphocytes and NK cells from healthy donors and HIV-1 infected patients. Flow cytometry analysis was performed on 100 μl of peripheral blood from A: healthy controls, B: avireamic HIV-1 infected patients, C: vireamic HIV infected patient, using fluorescent conjugated antibodies to CD3, CD8, CD56, CD94, and NKG2A. Analysis was performed on gated cells. D: Comparison of CD94/NKG2A expression in CD8+ T lymphocytes from healthy controls (open bar; n = 10), HIV-1 infected patients (vertical hatched bar; n = 46), avireamic HIV-1 infected patients (oblique hatched bar; n = 23) and vireamic HIV-1 infected patients (horizontal hatched bar; n = 23). Data represent the mean ± SEM of each group. The Mann-Whitney test was used to calculate significant differences between the different groups. **p < 0,01 significance of difference of CD94/NKG2A expression in CD8+ T cells between healthy controls vs HIV-1 infected patients; *p < 0,05 significance of difference of CD94/NKG2A expression in CD8+ T cells between HIV-1 infected avireamic patients vs vireamic patients.

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Retrovirology

ISSN: 1742-4690

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