Fig. 3
From: Repression of HIV-1 reactivation mediated by CRISPR/dCas9-KRAB in lymphoid and myeloid cell models
CRISPR LTR5 J.Lat 10.6 cells still promotes HIV-1 latency repression in the presence of HDAC inhibitors. A GFP expression of each sgRNA LTR5 transduced J.Lat 10.6 cells untreated. B GFP expression of sgRNA LTR5 transduced J.Lat 10.6 cells treated with 5 µM SAHA for 24 h. C GFP expression of sgRNA LTR5 transduced J.Lat 10.6 cells treated with 0.15 µM Panobinostat 24 h. The statistical analysis was done using Student-T test comparing mean LTR5 with NT (**p < 0.05; ***p < 0.0008). The mean values of two technical measures of three independent biological experiments are shown