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Table 2 Frequency of BST-2 Polymorphism in HIV-1 subtype C chronically infected cohort and uninfected cohorts of black South Africans

From: Bone marrow stromal antigen 2 (BST-2) genetic variants influence expression levels and disease outcome in HIV-1 chronically infected patients

SNP

 

Study population

HI vs HU

HIV infected (HI)

HIV uninfected (HU)

OR [95% CI]

p-value

MAF

 

n = 123 (%)

n = 20 (%)

  

rs919266

A

3 (1.2)

2 (5.0)

N/A

N/A

rs919267

T

95 (38.6)

14 (65.0)

0.29 [10.30–9.72]

< 0.0001

rs9576

A

25 (11.0)

4 (10.0)

N/A

N/A

rs919266

G/G

120 (97.6)

18 (90.0)

  

G/A

3 (2.4)

2 (10.0)

  

AA

0 (0.0)

0 (0.0)

 

rs919267

C/C

51 (41.5)

3 (15.0)

  

C/T

49 (39.8)

8 (40.0)

  

TT

23 (18.7)

9 (45.0)

  

rs9576

C/C

97 (79.5)

16 (80.0)

  

C/A

25 (20.5)

4 (20.0)

  

AA

0 (0.0)

0 (0.0)

  
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Retrovirology

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