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Fig. 1 | Retrovirology

Fig. 1

From: Bone marrow stromal antigen 2 (BST-2) genetic variants influence expression levels and disease outcome in HIV-1 chronically infected patients

Fig. 1

BST-2 expression levels in PBMCs and on CD4+ T cells from HIV-1 uninfected and infected participants. A BST-2 mRNA levels were compared between 20 HIV-1 uninfected (black squares) and 100 HIV-1 chronically infected participants (black circles) selected at baseline from the Sinikithemba chronic infection cohort. B A representative flow cytometry plots showing gating strategy for CD4+ T cell population from lymphocytes. Histograms show low (green), mid (blue) and high (orange) BST-2 expression intensity compared to the BST-2 FMO (red). C BST-2 surface staining on 20 HIV-1 uninfected (black squares) and 20 HIV-1 infected (black circles) participants. Horizontal lines within the clusters are depicting the median. Group comparisons of PBMCs and CD4+ T-cells were performed using the Mann–Whitney test

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