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Fig. 3 | Retrovirology

Fig. 3

From: Altered Env conformational dynamics as a mechanism of resistance to peptide-triazole HIV-1 inactivators

Fig. 3

Peptide triazole inhibition of HIV-1 pseudotyped with wild type or resistant Envs. The activities of AAR029b (A, C) and KR13 (B, D) were measured against Envs from NL4-3 (A, B) and HxBc2 strains (C, D) that contained the following mutations: S143N (red), V255I (green) V255T (purple), V255I/S143N (orange), V255T/S143N (black, open symbol). The wild type Env titration is shown in blue. Data represent mean and standard deviation of five independent experiments performed in triplicate. IC50 values are reported in Table 2

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Retrovirology

ISSN: 1742-4690

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