Fig. 1

Organization and structure of the HIV-1 capsid. A Schematic of a mature HIV-1 particle in cross-section, with protein layers labeled (generated from BioRender). B Geometric model for the arrangement of CA subunits in the mature viral capsid. The CA hexamers are colored green and pentamers blue. Diagram adapted from [16]. C Structure of the CA hexamer with bound IP6, rendered from pdb 6BHT [4]. Phosphate oxygens in IP6 are shown as red spheres