Fig. 3
Neutralisation of HIV-1 pseudoviruses by pN6. A Neutralisation by pN6 was assessed against a panel of 10 HIV-1 ENV pseudoviruses, and HIV-1 strain BaL.26 as an internal control, using TZM-bl cells. pN6 neutralisation assay was carried out in triplicate, and mN6 BaL.26 set was carried out in duplicate. B Correlation of published mN6 IC50s with pN6 IC50s from pseudovirus neutralisation assay. Open circle denotes assay-derived IC50 of pN6 compared with mN6 for BaL.26, rather than published value, as an internal control. Pearson correlation analysis calculated r value of 0.92 (p ≤ 0.0001)