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Fig. 5 | Retrovirology

Fig. 5

From: Comparative analysis of human microglial models for studies of HIV replication and pathogenesis

Fig. 5

Scatter plots comparing mRNA expression levels from microglia model systems. Signature comprised of 780 microglia-enriched genes are displayed as colored dots. Conserved gene expression is shown in red; genes more highly expressed in human adult microglia are shown in green, and genes more highly expressed in model systems are shown in blue (FC > 2, FDR ≤ 0.05). A panel of 15 core primary human adult microglia genes are labeled with text. a iPSC-MG vs Adult-MG, b MMG vs Adult-MG, c C20 vs Adult-MG, d HMC3 vs Adult-MG. e Stacked bar plot showing conservation and divergence of 780 primary human adult microglia enriched transcripts from putative microglia model systems. Red corresponds to conserved signatures with adult microglia (AMG), green are expressed at higher levels in AMG, blue at higher levels in the indicated model cell type

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