Fig. 3

Transmitted founder Envelopes induce more inflammatory immune response. Envelope clones (Env) were grouped according to time post-infection and the cytokine concentrations (pg/ml) secreted in response to transmitted founder (TF, grey bar) and chronic infection (CI, white bar) clones were compared to background. The fold change for each cytokine and chemokine above background for four biological repeats are indicated. Mann–Whitney t-test was used to compare the median value of the fold-change of cytokine concentration of four independent MDDC donors