Fig. 5

CDKN1A/p21 and ZC3H12A/MCPIP1 mRNA levels are positively correlated in total, HLA-DR⁻ and HIV-specific CD4⁺ T cells and primary monocytes. The ZC3H12A/MCPIP1 and isoform of CDKN1A/p21 (probe ILMN_1784602) normalized expression correlations were performed with data from previous studies in a, b total CD4⁺ T cells (GSE18233, GSE28128), c HLA-DR- CD4⁺ T cells (GSE23879), d HIV-specific CD4⁺ T cells and e, f primary monocytes (GSE52900, GSE18464) considering all groups (EC, VC, NC-TP, NC-LTNP, ART-suppressed, ART-non-suppressed, and HIV-negative subjects). The points’ colors indicate the patient group, accordingly to the legend. Correlation coefficients (Spearman’s ρ) are shown in the bottom right corner of each graph. P-values < 0.05 were considered statistically significant