| T20 (nM) IC50 ± SD | Ratio | p value |
---|---|---|---|
LAIwt | 138.34 ± 39.45 | 1.00 |  |
L544S | 8248 ± 682.35 | 59.62 | < 0.001 |
G547D | 1749.02 ± 233.44 | 12.64 | < 0.001 |
E560G | 61.71 ± 11.71 | 0.45 | 0.0057 |
L544S G547D | 25,310.03 ± 2985.82 | 182.96 | < 0.001 |
L544S E560G | 3006.20 ± 548.26 | 21.73 | < 0.001 |
G547D E560G | 1753.74 ± 340.63 | 12.68 | 0.0022 |
L544S G547D E560G | > 76,800 | > 555.16 | < 0.001 |
L544S G547D E560D | 31,012.25 ± 3364.73 | 224.18 | < 0.001 |