Fig. 9

Occupancy levels of AFF4 are elevated at genes that are upregulated upon FUS depletion. a + b AFF4 and Cdk9 ChIP-seq occupancy dataset from untreated cells focusing on genes that are affected due to loss of FUS expression (see also Additional file 1: Figure S3 for RNA seq). For each of the indicated windows, reads of Cdk9 or AFF4 were determined. *p < 0.0001 from Kruskal–Wallis test. c Fold of change in Cdk9 ChIP-seq reads within genes that were affected upon FUS depletion