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Table 1 Parameters linked to the development of broadly neutralizing antibodies

From: The role of follicular helper CD4 T cells in the development of HIV-1 specific broadly neutralizing antibody responses

Parameter References
Tfh  
 Frequency [50]
 Quality [50, 52, 61, 69]
 Phenotype / specificity [50, 61, 69]
B-cells  
 Precursor frequency [40, 94, 95, 97, 106, 107, 116]
 BCR affinity for antigen [37, 40, 107]
 Isotype class [98]
 Amount of help received by Tfh [36, 40, 44, 52]
Antigen  
 Persistence [76, 106]
 Diversity [69]
Tregs/Tfr  
 Frequency [53, 90, 91]