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Fig. 7 | Retrovirology

Fig. 7

From: CD8+ T cells specific for conserved, cross-reactive Gag epitopes with strong ability to suppress HIV-1 replication

Fig. 7

Recognition of mutant epitope peptides by T cells in HIV-1-infected individuals. a Frequencies of TL8 and HR10 mutant epitopes in Japanese individuals. The frequencies of mutant epitopes were investigated from 430 chronically HIV-1-infected Japanese individuals. b The CD8+ T-cell responses to the index and mutant epitope peptides in HIV-1-infected Japanese individuals were analyzed by using an IFN-γ ELISPOT assay. The results are shown as mean and SD (n = 3). c The responses of the T cell-lines specific for TL8 or HR10 to wild-type or mutant peptide-prepulsed 721.221 cells expressing the corresponding HLA alleles were analyzed by using the ICS assay. The results are shown as mean and SD (n = 3)

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Retrovirology

ISSN: 1742-4690

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