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Table 1 PERV infection experiments using cultured cells of different species

From: Why was PERV not transmitted during preclinical and clinical xenotransplantation trials and after inoculation of animals?

Type of infection Species References
Productive infection with replicationa Immortalised human cells (e.g., 293 cells), cat, mink [28, 34,35,36,37,38,39]
Infection without replicationb Primary human cells (e.g., PBMCsd, PAEC), rhesus monkey, baboon, gorilla, chimpanzeed [28, 35, 37,38,39,40,41,42,43]
Absence of infectionc Mouse, rat, rabbit, cotton rat, horse, pig-tailed macaque, African green monkeys, cynomolgus monkeys [28, 38, 44,45,46]
  1. aRelease of more virus particles than used for infection
  2. bRelease of less virus particles than used for infection
  3. cAbsence of provirus integration
  4. dUsing human-adapted PERV
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