Fig. 4

Fasnall inhibits HIV-1 replication. a Extracellular p24 levels in TZM-bl cells 48 h post infection (black dots ± SD, n = 3, black line), without significant effects on TZM-bl cell viability (i.e. mean MTT-activity; open circles, n = 3) b Fasnall and C75, each at 10 µM, significantly reduce HIV-1 replication in primary PBMC, as measured by p24 production. The data presented are mean values (± SD) from three independent experiments. ** indicates p < 0.0001, treatment versus DMSO-treated control (Students t test), c PBMC viability after treatment with Fasnall as measured by propidium iodide staining (dotted line drawn at 85%)