Fig. 3

Anti-HERV-K (HML-2) antibodies in HIV infection. The detection of total IgG against HERV-K (HML-2) gag was performed for 40 seronegative low risk healthy donors (SNLR white dots) and 80 chronically HIV infected subjects (HIV black dots) by peptide-based ELISA using sequences determined in Fig. 2 and represented by their number on the top of each graph (a–h). Each graph represents ELISA for one linear epitope. Error bars represent SEM. The statistical significance between the different groups was established using the Mann–Whitney u test. The figure shows the representative results of at least three independent experiments. A p value <0.05 was considered as significant. *p < 0.05; **p < 0.01; ***p < 0.001. In parenthesis is indicated the adjusted p value (q) regarding the 3 independent experiments using original method of Benjamini and Hochberg with a Q of 5%. The number of independent observations is represented by n