Effects of host restriction factors and the HTLV-1 subtype on susceptibility to HTLV-1-associated myelopathy/tropical spastic paraparesis

Table 4 HTLV-1 provirus sequences in familial HAM/TSP by paired analysis

Family	Relationships	HTLV-1 subtypes	Number of variants within family
1	Parent–child	Transcontinental	0
2	Parent–child	Transcontinental	0
3	Siblings	Transcontinental	1
4	Siblings	Japanese	1
5	Siblings	Japanese	2
6	Siblings	Japanese	2
7^a	Siblings	Japanese	35
8	Siblings	Japanese	1
9	Relatives	Japanese	3
10	Parent–child	Japanese	0

Both patients in Family 1–9 were developed with HAM/TSP, and in Family 10 one were affected with HAM/TSP and the other with HTLV-1 carrier
^aOne in Family 7 was affected with adult T-cell lymphoma in addition to HAM/TSP

ISSN: 1742-4690