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Fig. 9 | Retrovirology

Fig. 9

From: Conserved residues within the HIV-1 Vpu transmembrane-proximal hinge region modulate BST2 binding and antagonism

Fig. 9

E28 residue is a key modulator of binding of Vpu to BST2. Co-IP following co-transfection of HEK293T cells with a proviral construct encoding WT Vpu, E28A/L33A or E28A Vpu mutants and a BST2 expressor. Below the blot is the extent of BST2 binding of each Vpu mutant, relative to WT Vpu (set at 100%). BST2 binding efficiency was determined as indicated in Fig. 5 legend

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Retrovirology

ISSN: 1742-4690

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