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Fig. 6 | Retrovirology

Fig. 6

From: HIV signaling through CD4 and CCR5 activates Rho family GTPases that are required for optimal infection of primary CD4+ T cells

Fig. 6

Canonical Rho signaling pathways were identified in a phosphoproteomics screen of HIV-1 signaling via CD4 and CCR5. Phosphoproteomic analysis reveals that numerous Rho family GTPase and ROCK signaling members are dysregulated (purple) in response to HIV exposure compared with a similarly prepared microvesicle control. Network analysis was performed using Ingenuity Pathway Analysis software

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Retrovirology

ISSN: 1742-4690

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