Fig. 7
From: Antibody-dependent CD56+ T cell responses are functionally impaired in long-term HIV-1 infection
MMP inhibitor GM6001 partially restored the impaired ADCC capacity mediated by DN CD56+ T subset of HIV-1+ subjects. a CD16 MFI on DN CD16+ CD56+ T cells were compared between HIV+ patients (n = 10) and healthy controls (n = 10). b CD16 MFI on DN CD56+ T cells activated by IL-2+ DMSO and IL-2+ GM6001 for 0, 3, 6, 12 h. c CD107 expression and IFNγ production of DN subset from HIV+ patients (n = 10) activated by P815+ DMSO, P815+ Ab+ DMSO and P815+ Ab+ GM6001 were determined by flow cytometry. d The percentage of CD107a+ CD56+ T cells and IFNγ+ CD56+ T cells activated by Ab-bound P815 cells in the presence or absence of GM6001 from HIV-1+ subjects (n = 10)