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Table 2 IC50, IDV, relative change in IC50 compared to NL4-3 susceptibility

From: The HIV-1 late domain-2 S40A polymorphism in antiretroviral (or ART)-exposed individuals influences protease inhibitor susceptibility

IC50 nM

WT

NL4-3-S40A

NL4-3-S40F

NL4-3 multi-drug resistant strain

Expt 1

1.0

0.94

1.0

20.0

Expt 2

1.0

0.70

0.90

22.6

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Retrovirology

ISSN: 1742-4690

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