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Table 1 Relative occurrence of non-conserved cysteine residues in V1, V2 and V4 in HIV-1 subtypes

From: HIV-1 escapes from N332-directed antibody neutralization in an elite neutralizer by envelope glycoprotein elongation and introduction of unusual disulfide bonds

HIV-1 subtype na V1 region V2 region V4 region
Canonicalb Plus 2 cysteines Plus 4 cysteines Total Normal 2 cysteines 4 cysteines Total Canonical Plus 2 cysteines Plus 4 cysteines Total
A 208 98.6 1.4 0 100 99.5 0.5 0 100 100 0 0 100
B 1338 94.4 5.5 0.1 100 99.9 0.1 0.1 100 99.9 0.1 0 100
C 952 94.5 5.1 0.3 100 99.7 0.3 0 100 99.5 0.5 0 100
D 101 99 1.0 0 100 100 0 0 100 100 0 0 100
F 39 100 0.0 0 100 100 0 0 100 100 0 0 100
G 61 73.8 26.2 0 100 100 0 0 100 100 0 0 100
Other 960 96.9 3.1 0 100 99.6 0.4 0 100 89.5 10.5 0 100
Total 3659 95.2 4.7 0.1 100 99.7 0.2 0 100 97.1 2.9 0 100
  1. aThe number of Env sequences used to calculate the percentage of viruses with canonical or non-conserved cysteine residues per subtype
  2. bThe percentage of viruses with normal or non-conserved cysteine residue