Fig. 2

Alterations in β7⁺ CD4⁺ T cells homing to the gut is higher in patients who started cART late and is conversely correlated to the decrease of the ratio CD4⁺/CD8⁺ T cells. Correlation between the ratio blood/rectum of β7 expression in CD4⁺ T cells and the number of CD4⁺ T cells at the initiation of cART (a) and with the ratio CD4⁺/CD8⁺ T cells in blood (b). Flow cytometry analysis of β7 expression in CD4⁺ T cells in blood and in rectum of two HIV-infected individual representatives of “high” and “low-level CD4 group” respectively (c). Gating strategy: lymphoid cells were gated using the FSC/SSC parameters. Then, T cells were gated by their expression of CD3 and were separated in CD4⁺ and CD8⁺ T cells by the CD4 expression and β7expression was studied in CD4⁺ T cells. Each symbol represents an individual