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Table 1 Conservation of V3 loop residues in HIV Env sequences from the Los Alamos database for A) all clades and B) clade CRF02_AG

From: Mechanisms of escape from the PGT128 family of anti-HIV broadly neutralizing antibodies

A: All clades
Position Donor 36 1 2 3 4
295 N N* (50.2) I (12.9) V (12.6) T (8.8)
301 N* N* (79.1) N (10.5) G (2.1) T (1.4)
307 V I (61.4) V (16.8) S (8.8) M (3.7)
308 H R (34.9) H (25.1) I (8.6) T (6.9)
320 G G (75.1) T (8.1) N (6.2) E (2.7)
321 E D (45.0) E (22.7) A (7.2) Q (5.5)
322 V I (89.4) V (6.9) G (1.0) T (0.4)
325 N D (78.3) N (16.9) I (1.2) K (0.8)
326 P I (94.6) T (1.2) G (1.0) P (0.8)
330 F H (68.9) Y (25.7) F (1.8) Q (1.1)
332 T N* (69.9) E (8.5) T (5.9) N (4.8)
334 N* S (69.4) N* (23.2) T (2.8) N (2.2)
  1. Values are based on 4907 and 121 sequences from the Los Alamos database for all clades and clade CRF02_AG respectively. Values are reported as  % occurrence and only the four most frequent residues are shown. N* refers to asparagine residues that are part of a glycosylation sequon and N refers to asparagine residues that are not
B: clade CRF02_AG
Position Donor 36 1 2 3 4
295 N N* (68.6) T (10.7) I (9.1) N (4.1)
301 N* N* (83.4) N (5.8) G (3.3) K (1.6)
307 V V (62.8) I (21.5) S (6.1) G (2.5)
308 H R (64.5) H (20.7) V (5.8) M (1.7)
320 G G (81.8) T (6.6) N (3.3) D (3.3)
321 E D (56.2) E (21.5) A (7.4) G (5.0)
322 V I (90.1) V (7.4) T (0.8) Y (0.8)
325 N D (71.9) N (24.0) G (2.5) K (1.7)
326 P I (96.7) D (1.7) T (0.8) K (0.8)
330 F H (74.4) Y (21.5) S (1.7) Q (0.8)
332 T N* (81.0) T (6.6) N (4.1) K (1.7)
334 N* S (81.8) N* (14.9) T (1.7) V (0.8)
  1. Values are based on 4907 and 121 sequences from the Los Alamos database for all clades and clade CRF02_AG respectively. Values are reported as  % occurrence and only the four most frequent residues are shown. N* refers to asparagine residues that are part of a glycosylation sequon and N refers to asparagine residues that are not