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Table 1 Outcome of FeLV infection in the two FeLV-exposed blood donors and the ten exposed recipient cats

From: Retroviral DNA—the silent winner: blood transfusion containing latent feline leukemia provirus causes infection and disease in naïve recipient cats

 

Group

Cat

Outcome of FeLV exposure

Health status long-term follow-upa

Blood donors

A

DP

Regressive infection, provirus-positive

Healthy

 

B

DR

Regressive infection, viral plasma RNA- and provirus-positive

Week 60: reactivation of infection, multicentric T-cell lymphomab

Recipients

A

P1

Progressive infection, persistently p27-positive

Week 31: non-regenerative anemia (FeLV-C)b

  

P2

Progressive infection, persistently p27-positive

Week 84: multicentric T-cell lymphomab,c

  

P3

Regressive infection, provirus-positive

Week 94: feline lower urinary tract disease (FLUTD)

  

P4

Regressive infection, provirus-positive

Healthy

  

P5

Regressive infection, provirus-positive

Week 133: reactivation of infection, multicentric T-cell lymphomab

 

B

R1

Regressive infection, provirus-positive

Week 26: reactivation of infection, multicentric T-cell lymphoma with secondary lymphoblastic leukemiab

  

R2

Regressive infection, provirus-positive

Healthy

  

R3

Regressive infection, provirus-positive

Healthy

  

R4

Regressive infection, provirus-positive

Week 28: multicentric T-cell lymphoma; no reactivation of the infection (p27-negative)b

  

R5

Regressive infection, provirus-positive

Healthy

  1. euthanized/died
  2. aStatus observed until 149 weeks post transfusion
  3. bEuthanized for humane reasons
  4. cDuring follow-up study, without re-exposure to FeLV [35]