Fig. 6
A1752 generates aberrant Gag protein processing. The virus particles produced from MT-4 cells in the presence of A1752 (a, d), and from 293FT cells transfected with HIV-1 proviral plasmid and treated with the indicated inhibitors (b–c) were analyzed using western blot assay. The membranes were probed with either anti-Gag (a, d), −NC (b) or −CA (c, d) antibodies as indicated, respectively. A CA-NC and CASP1 form (25 KD) of Gag protein expressed in E. coli were used as a control. Double asterisk indicates a specific major protein band (30 kD) generated by A1752