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Fig. 2 | Retrovirology

Fig. 2

From: Increased susceptibility of CD4+ T cells from elderly individuals to HIV-1 infection and apoptosis is associated with reduced CD4 and enhanced CXCR4 and FAS surface expression levels

Fig. 2

CD4+ T cells from elderly individuals respond poorly to TCR-CD3 stimulation and express increased levels of MHC-I. a–d Representative primary data and statistical evaluation of the expression levels of a, c CD69 (early activation marker) and b, d CD25 (late activation marker) on unstimulated (a, b) or CD3/CD28 bead stimulated (c, d) CD4+ T cells from young (Y) and elderly (O) blood donors. e–h Expression levels of e TCR-CD3, f CTLA-4, g CD28 and h MHC-I on unstimulated or CD3/CD28 bead stimulated CD4+ T cells from young and old donors

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