Fig. 7
From: Conserved determinants of lentiviral genome dimerization
NC binding promotes dimer formation. a Secondary structures of NC proteins for HIV-1NL4-3, SIVcpzUS, SIVcpzTAN1, and HIV-2ROD. The zinc fingers motifs (CCHC, red) are strictly conserved among selected viral strains. b–e Native agarose gel NC titration results obtained for HIV-1NL4-3, SIVcpzUS, SIVcpzTAN1, and HIV-2ROD 5′-LWT in PI buffer. Addition of 0, 5, 10 equivalents of NC to the respective retroviral 5′-leader RNAs was probed using TB and TBM running buffers. Monomers (M) and dimers (D) are indicated