Fig. 7
From: Apoptosis-induced activation of HIV-1 in latently infected cell lines
Apoptosis induced HIV-1 reactivation kinetics. The time course of HIV-1 activation study was determined in ACH-2 cells (a and b) and U1 cells (c and d) after treatment with apoptosis inducing agent. The cells were harvested at the indicated time-points (0, 2, 4, 8, 18, 24, and 48 h) and assayed for apoptosis (a and c) by Annexin-V staining and HIV-1 activation was quantitated by RT-qPCR for HIV-1 unspliced RNA (b and d). Cells treated with PMA (for U1 cells) and TNF-α (for ACH-2) were used as positive controls