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Table 1 The potency of LEDGINs is not affected by the presence of LEDGF/p75 HIV producer cells

From: HIV-1 IN/Pol recruits LEDGF/p75 into viral particles

Producer cell line EC 50 CX05045 (μM) 1
WT 0.6 (95% CI: 0.5-0.8)
LEDGF/p75KD 0.8 (95% CI: 0.6-1)
  1. 1Effective concentration in μM required to reduce Tat-driven firefly luciferase activity by 50% in TZM-bl cells at 40 hpi. The table shows means and the 95% confidence interval (95%CI).