Figure 6
From: Griffithsin tandemers: flexible and potent lectin inhibitors of the human immunodeficiency virus
Location of GRFT binding-associated oligosaccharides (coupled to Asn234, Asn295, and Asn448) in the context of HIV trimeric spike. Disaccharide modification of Asn234 (blue), Asn295 (red) and Asn448 (yellow) are displayed on a gp120 trimer. X-ray crystal structure of the partially glycosylated HIV-1HXBc2 gp120 (PDB 1GC1 [45]) was superimposed on unliganded gp120 electron tomography structure (PDB 3DNN [34]).