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Figure 2 | Retrovirology

Figure 2

From: Emergence of CD134 cysteine-rich domain 2 (CRD2)-independent strains of feline immunodeficiency virus (FIV) is associated with disease progression in naturally infected cats

Figure 2

CRD2-independent Env variants were isolated more frequently from cats displaying signs of immunodeficiency and disease progression. Cats were classified into 3 groups: 1) alive/deceased, 2) clinically healthy/sick, 3) CD4+ T cell counts > or <350 cells/μl. Cats which died during the study, displayed clinical signs (sick) or had CD4+ T cell counts <350 cells/μl were more likely to harbour at least one CRD2-independent variant (chequered bars). Conversely, CRD2-dependent variants were associated with the alive, clinically healthy cats with CD4+ T cell counts >350 cells/μl (grey bars). P-values (Fisher’s exact test) were shown below the x-axis.

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