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Figure 5 | Retrovirology

Figure 5

From: HIV-1 Vif inhibits G to A hypermutations catalyzed by virus-encapsidated APOBEC3G to maintain HIV-1 infectivity

Figure 5

HXB2N virus replicates more efficiently than HXB2NΔVif or HXB2B3 in Jurkat cell lines stably expressing HAA3G22K. Jurkat cells stably expressing A3G or HAA3G22K were analyzed by Western blot (A). Virus derived from HXB2N, HXB2NΔVif or HXB2B3 was used to infect Jurkat (B), Jurkat/A3G (C) and Jurkat/HAA3G22K (D) stable cell lines. Viral supernatants were harvested on days 1, 3, 5 and 7 post-infection and analyzed by p24 ELISA to measure HIV-1 levels.

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Retrovirology

ISSN: 1742-4690

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