Figure 6

Association of surface CD25 and CD69 expression on B cells with intracellular IL-6 expression. The percentages of total, naïve and memory (CD27+) B cells expressing CD25 and CD69 were correlated with cells expressing intracellular IL-6 following in vitro stimulation with CpG and CD40L. Specimens from 60 individuals are included in the analysis: 21 HIV-1 infected individuals naïve to treatment, 19 HIV-1 infected patients on ART and 20 age matched controls. The P values were derived using the Spearman correlation test.