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Table 2 Statistical comparison of key clinical and demographic parameters across study groups

From: Single genome analysis reveals genetic characteristics of Neuroadaptation across HIV-1 envelope

Groups

NCN

ANI + MND

p-value

# Male Sex/total

6/6

8/9

N/A

# Men who have sex with men/total

5/6

7/9

N/A

Mean Age (years, range)

44 (41-52)

45 (32-62)

0.72

Mean Years of Education (years, range)

13 (10-16)

14 (9-18)

0.31

Mean Est. duration of infection (months, range)

118 (49-214)

99 (27-212)

0.46

Mean CD4+ T cell count (cells/mm3, range)

618 (418-802)

420 (220-819)

0.09

Mean CD4+ T cell nadir (cells/mm3, range)

433 (297-554)

333 (215-537)

0.15

Mean plasma HIV-1 RNA (log copies/mL, range)

4.3 (2.9-4.8)

4.3 (3.3-4.7)

1.00

Mean CSF HIV-1 RNA (log copies/mL, range)

3.9 (2.1-4.3)

3.4 (2.1-3.8)

0.52

  1. All p-values determined by Mann Whitney test. For all comparisons, p-values <0.05 are considered significant.