Volume 9 Supplement 1

Abstracts from the 17th International Symposium on HIV and Emerging Infectious Diseases (ISHEID)

Open Access

HBV and HCV genotypes distribution on the territory of Belarus

Retrovirology20129(Suppl 1):P57

https://doi.org/10.1186/1742-4690-9-S1-P57

Published: 25 May 2012

Materials and methods

236 HCV and 158 HBV plasma samples collected during 2004-2011 have been investigated. EIA, PCR, RT-PCR, sequencing, SeqScape, BioEdit, MEGA4.1, statistica v.6 software have been used.

Results

Of 158 HBV HBsAg positive specimens 17 (10,8%) were from patients with acute hepatitis B and 141 (89,2%) from chronic hepatitis B. Among surveyed were 83 (43,6%) women and 92 (56,4%) men at the age from 15 till 90 years. Middle age has made 44,5±17,8 years. From 158 surveyed 11 persons have been HBV+HBC co-infected and 1 with HBV+HCV+HIV. HBV genotypes has been defined at 61 (34,9%) patient. The phylogenetic analysis of HBV preS fragment has shown that in 52 (85,3%) cases come to light D genotype (D1 – 32.9%; D2 - 26,2%, D3 – 26.2%), in 7 (11,5%) – A (A2) and in 2 (3,2%) – C (C2) genotype. Of 236 HCV infected patients prevailed 1b (53,8%, n=127) and 3a (28,8%, n=58) genotypes. At 30 (12.7%) cases have been revealed 1a genotype and 2a and 2b genotypes have been revealed in 8 (3,4%) and 3 (1,3%) cases accordingly.

Conclusion

In the territory of Belarus a genetic variety of HBV and HCV genotypes, caused both circulation before the brought viruses, and new drifts from neighbouring countries, basically from Russia and Ukraine is observed.

Authors’ Affiliations

(1)
Briem

Copyright

© Gasich et al; licensee BioMed Central Ltd. 2012

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Advertisement