Figure 1From: The W100 pocket on HIV-1 gp120 penetrated by b12 is not a target for other CD4bs monoclonal antibodiesProximal gp120 residues T373 and N386 (red) surround the pocket penetrated by the organic rings of b12's W100 (yellow). The longer side chain of R373 in combination with the glycan (orange) at N386 may block the pocket and prevent b12 (green) binding.Back to article page