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Figure 1 | Retrovirology

Figure 1

From: Clinical, virological and biochemical evidence supporting the association of HIV-1 reverse transcriptase polymorphism R284K and thymidine analogue resistance mutations M41L, L210W and T215Y in patients failing tenofovir/emtricitabine therapy

Figure 1

Principal axis factoring analysis of correlations between mutations associated with tenofovir/emtricitabine therapy failure. A factor scores plot (in rotated factor space) is shown. Amino acid changes with high coefficients of covariation are close together, while large distances separate those substitutions that show low or negative coefficients of association. Major mutations of the TAM1 and TAM2 complexes are indicated in red and blue, respectively.

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