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Table 5 Expression of hA3B in 293 T cells infected with XMRV/MX did not affect viral infectivity

From: Moloney murine leukemia virus glyco-gag facilitates xenotropic murine leukemia virus-related virus replication through human APOBEC3-independent mechanisms

Donor cells Trial 1 Trial 2 Trial 3 Trial 4 Ave ± Std
ICs/ml* ICs/ml ICs/ml ICs/ml ICs/ml Relative infectivity**
293T/XMRV/pcDNA3 7.0 X 104 l.3 X l05 l.5 X 105 1.5 X 105 l.2 ± 0.37 X l05 1 ± 0
293T/XMRV/hA3B 8.5 X 104 l.0 X l05 l.4 X l05 l.2 X l05 1.1 ± 0.23 X l05 0.931 ± 0.185
293T/MX/pcDNA3 8.4 X 105 1.4 X 106 3.2 X 106 3.3 X 106 2.2 ± 1.2 X 106 16.7 ± 5.91
293T/MX/hA3B 1.0 X 106 l.9 X 106 4.1 X 106 3.3 X 106 2.6 ± 1.4 X 106 19.8 ± 6.22
  1. The infected 293 T cells were transfected with the plasmid encoding HA-tagged hA3B plasmids (293 T/XMRV/hA3B and 239 T/MX/hA3B) or control plasmids (293 T/XMRV/pcDNA3 and 293 T/MX/pcDNA3). HeLa cells were infected with XMRV released from the viral producing cells described above. *The infectious units (IU) were measured from the number of infectious centers that was normalized by the amount of Capsid in viruses and IU per ml was shown. **The relative infectivity to the HeLa cells infected with the virus released from 293 T/XMRV/pcDNA cells was shown.